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Journal of Dental Research
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Laser-Matrix-Fluoride Effects on Enamel Demineralization

C.-Y.S. Hsu

Department of Preventive Dentistry, Faculty of Dentistry, National University of Singapore, Singapore 119074

T.H. Jordan

Department of Chemistry, Cornell College, Mount Vernon, IA 52314, USA

D.N. Dederich

Department of Periodontics, LSUMC School of Dentistry, New Orleans, LA 70019, USA

J.S. Wefel

Dows Institute for Dental Research, College of Dentistry, University of Iowa, Iowa City, IA 52242, USA, wefel-james{at}uiowa.edu

Laser and fluoride have been shown to inhibit enamel demineralization. However, the role of organic matrix and their interactions remains unclear. This study investigated the interaction among CO2 laser irradiation, fluoride, and the organic matrix on the demineralization of human enamel. Twenty-four molars were selected and cut into halves. One half of each tooth was depleted of its lipid and protein. The other half served as a matched control. Each tooth half had two window areas, treated with a 2.0% NaF gel. All left windows then received a laser treatment. Next, the tooth halves were subjected to a four-day pH-cycling procedure that created caries-like lesions. Tooth sections were cut from the windows, and microradiographs were used for quantification of the demineralization. The combined fluoride-laser treatment led to 98.3% and 95.1% reductions in mineral loss for enamel with and without organic matrix, respectively, when compared with sound enamel.

Key Words: CO2 laser • organic matrix • fluoride • enamel demineralization.

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Journal of Dental Research, Vol. 80, No. 9, 1797-1801 (2001)
DOI: 10.1177/00220345010800090501


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This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
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Citing Articles
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Right arrow Articles by Hsu, C.-Y.S.
Right arrow Articles by Wefel, J.S.
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PubMed
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What's this?