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No Heritability of Temporomandibular Joint Signs and Symptoms

Oral Health Clinical Research Center, University of Minnesota School of Dentistry, 17-116 Moos Tower, 515 Delaware Street S.E., Minneapolis, MN 55455, USA, micha002{at}tc.umn.edu

B.L. Pihlstrom

Oral Health Clinical Research Center, University of Minnesota School of Dentistry, 17-116 Moos Tower, 515 Delaware Street S.E., Minneapolis, MN 55455, USA

J.S. Hodges

Oral Health Clinical Research Center, University of Minnesota School of Dentistry, 17-116 Moos Tower, 515 Delaware Street S.E., Minneapolis, MN 55455, USA

T.J. Bouchard, JR

Departmcnt of Psychology, University of Minnesota College of Liberal Arts, N249 Elliott Hall, 75 East River Road, Minneapolis, MN 55455, USA

The causes of temporomandibular joint (TMJ)-rclatcd signs and symptoms are largely unknown. We tested the hypotheses that these signs and symptoms, as well as oral parafunctional habits, are substantially heritable. Questionnaire and clinical data were collected from 494 twins, including pairs of reared-apart and reared-together monozygotic (MZ) and dizygotic (DZ) twins. A history of joint-area pain, joint noises, and clenching and grinding habits was scorcd as present or absent. Twenty-nine percent of the population experienced at least one sign or symptom. Nearly one-quarter of subjects clenched or ground their teeth, and 8.7% reported a history of joint-area pain. Pain was associated with clenching, grinding, and joint noises. MZ twins were no more similar than DZ twins for any outcome, suggesting that genetic factors do not influence these traits in the population. Reared-together MZ twins were no more similar than reared-apart MZ twins, suggesting a negligible effect of the family environment on these outcomes. Environmental factors unique to each twin appeared to be the major determinants of variation in this population.

Key Words: temporomandibular joint • twins • genetics • epidemiology.

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Journal of Dental Research, Vol. 79, No. 8, 1573-1578 (2000)
DOI: 10.1177/00220345000790080801


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Michalowicz, B.S. Articles by Bouchard, T.J. Search for Related Content PubMed PubMed Citation Articles by Michalowicz, B.S. Articles by Bouchard, T.J., JR Pubmed/NCBI databases Medline Plus Health Information Joint Disorders Temporomandibular Joint Dysfunction Social Bookmarking                         What's this?