Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Journal of Dental Research
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Bawden, J.W.
Right arrow Articles by LeGeros, R.Z.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bawden, J.W.
Right arrow Articles by LeGeros, R.Z.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Consideration of Possible Biologic Mechanisms of Fluorosis

J.W. Bawden

The Department of Pediatric Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, North Carolina 27599

M.A. Crenshaw

The Department of Pediatric Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, North Carolina 27599

J.T. Wright

The Department of Pediatric Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, North Carolina 27599

R.Z. LeGeros

The College of Dentistry, New York University, 345 E. 24th St., New York, New York 10010

Key Words: fluorides • fluorosis • enamel • zone refinement • isotopic exchange

REFERENCES

  • Aoba T., Fukae M., Tanabe T., Shimizu M., Moreno EC (1987a). Selective absorption of porcine-amelogenins onto hydroxyapatite and their inhibitory activity on hydroxyapatite growth in supersaturated solutions. Calcif Tissue Int 41:281-289.[Medline] [Order article via Infotrieve]
  • Aoba T., Tanabe T., Moreno EC (1987b). Function of amelogenins in porcine enamel mineralization during the secretory stage of amelogenesis. Adv Dent Res 1:252-260.[Abstract/Free Full Text]
  • Bawden JW, Keels MA, Deaton TG, Crenshaw MA (1988). The Ca, P, F, and proline content of developing bovine enamel under GBHA-stained and unstained bands. J Dent Res 67:938-941.
  • Brunelle JA, Carlos JP (1982). Changes in the prevalence of dental caries in U.S schoolchildren, 1961-1980. J Dent Res 61(Spec Iss):1346-1351.
  • Creath CJ, Eick JD, Hicks EP (1989). Effects of systemic fluoride on rat molar morphology. Caries Res 23:26-31.[Medline] [Order article via Infotrieve]
  • Crenshaw MA, Bawden JW (1984). Proteolytic activity in embryonic bovine secretory enamel. In: Tooth enamel IV. Fearnhead RW, Suga S, editors. Amsterdam, The Netherlands: Elsevier Science, pp. 109-113.
  • DenBesten PK (1986). Effects of fluoride on protein secretion and removal during enamel development in the rat. J Dent Res 65:1272-1277.
  • DenBesten PK, Crenshaw MA (1984). The effects of chronic high fluoride levels on forming enamel in the rat. Arch Oral Biol 29:675-679.[Medline] [Order article via Infotrieve]
  • DenBesten PK, Heffernan LM (1989a). Separation by PAGE of multiple proteases present in rat and bovine enamel. Arch Oral Biol 34:399-404.[CrossRef][Medline] [Order article via Infotrieve]
  • DenBesten PK, Heffernan LM (1989b). Enamel proteases in secretory and maturation incisor enamel of rats ingesting 0 and 100 ppm fluoride in drinking water. Adv Dent Res 3:199-202.[Abstract/Free Full Text]
  • DenBesten PK, Thariani H. (1992). Biological mechanisms of fluorosis and level and timing of systemic exposure to fluoride with respect to fluorosis. J Dent Res 71:1238-1243. DenBesten PK, Crenshaw MA, Wilson MH (1985). Fluoride-induced changes in the modulation of maturation stage ameloblasts of rats. J Dent Res 64:1365-1370.
  • Fejerskov O., Johnson N., Silverstone L. (1974). The ultrastructure of fluorosed enamel. Scand J Dent Res 82:357-372. Fejerskov O., Josephsen K., Larsen MJ, Thylstrup A. (1980). Cytological features of rat ameloblasts following long-term
  • fluoride exposure. Caries Res 14:181-182.
  • Fejerskov O., Manji F., Baelum V. (1990). The nature and mechanisms of dental fluorosis in man. J Dent Res 69:692-700.[Medline] [Order article via Infotrieve]
  • Graves RC, Stamm JW (1985). Oral health status in the United States: prevalence of dental caries. J Dent Educ 49:341-351. Heifetz SB, Driscoll WS, Horowitz HS, Kingman A. (1988). Prevalence of dental caries and dental fluorosis in areas with optimal and above-optimal water-fluoride concentrations. J Am Dent Assoc 116:490-495.[Abstract]
  • Kashiwa HK (1970). Calcium phosphate in osteogenic cells. Clin Orthop Rel Res 70:200-211.[Medline] [Order article via Infotrieve]
  • Kumar JV, Green EL, Wallace W., Carnahan T. (1989). Trends in dental fluorosis and dental caries prevalence in Newburg and Kingston, NY. Am J Publ Health 790:565-569.
  • LeGeros RZ (1983). Ultrastructural properties of human enamel apatite. In: Handbook of experimental aspects of oral biochemistry. Lazzari P, editor. Boca Raton, FL: CRC Press, pp. 159-179.
  • LeGeros RZ (1984). Incorporation of magnesium in synthetic and in biological apatites. In: Tooth enamel IV. Fearnhead RW, Suga S, editors. Amsterdam, The Netherlands: Elsevier Science Publishers B.V., pp. 32-36.
  • LeGeros RZ (1991). Calcium phosphates in oral biology and medicine. In: Monogr in oral science. Vol. 15. Basel: Karger. LeGeros RZ, Tung MS (1983). Chemical stability of carbonate and fluoride containing apatites. Caries Res 17:419-429. LeGeros RZ, Kijkowska T., Jia WT, LeGeros JP (1988). Fluoride-cation interaction in the formation and stability of apatites. J Fluor Chem 41:53-64.
  • LeGeros RZ, Daculsi G., Orly I., Abergas T., Torres W. (1989). Solution-mediated transformation of octacalcium phosphate (OCP) to apatite. Scan Electr Microsc 3:129-138. Leverett DH (1982). Fluorides and the changing prevalence of dental caries. Science 217:26-30.[Abstract/Free Full Text]
  • Leverett DH (1986). Prevalence of dental fluorosis in fluoridated and non-fluoridated communities-a preliminary investigation. J Publ Health Dent 46:184-187.
  • Leverett DH (1991). Appropriate uses of systemic fluoride: considerations for the 90s. J Publ Health Dent 51:42-47. Lovius BBJ, Goose DH (1969). The effect of water fluoridation on tooth morphology. Br Dent J 127:322-324.[Medline] [Order article via Infotrieve]
  • Mayer I., Schneider S., Sydney-Zax M., Deutsch D. (1990). Thermal decomposition of developing enamel. Calcif Tissue Int 46:254-257.[CrossRef][Medline] [Order article via Infotrieve]
  • Milhaud GE, Charles E., Loubiere M-L., Kolf-Clauw M., Joubert C. (1992). Effects of fluoride on secretory and postsecretory phases of enamel formation in sheep molars. Am J Vet Res 53:1241-1247.[Medline] [Order article via Infotrieve]
  • Moran RA, Deaton TG, Bawden JW (1995). Problems associated with estimation of net calcium uptake during enamel formation using 45Ca. J Dent Res (accepted for publication). Overall CM, Limeback H (1988). Identification and characterization of enamel proteinases isolated from developing enamel. Biochem J 256:965-972.
  • Patterson CM, Basford KE, Kruger BJ (1976). The effect of fluoride on the immature enamel matrix protein of the rat.
  • Arch Oral Biol 21:131-132.
  • Pendrys DG, Stamm JW (1990). Relationship of total fluoride intake to beneficial effects and enamel fluorosis. J Dent Res 69(Spec Iss):529-538.[Medline] [Order article via Infotrieve]
  • Robinson C., Kirkham J. (1990). The effect of fluoride on the developing mineralized tissues. J Dent Res 69:685-691. Sasaki S., Takagi T., Suzuki M. (1991a). Cyclic changes in pH in bovine developing enamel as sequential bands. Arch Oral Biol 36:227-231.[Medline] [Order article via Infotrieve]
  • Sasaki S., Takagi T., Suzuki M. (1991b). Amelogenin degredation by an enzyme having acidic pH optimum and the presence of acidic zones in developing bovine enamel.
  • In: Mechanisms and phylogeny of mineralization in biologic systems. Suga S, Nakahara H, editors. Tokyo: Springer-Verlag, pp. 79-81.
  • Segreto VA, Camman D., Collins EM, Smith CT (1984). A current study of mottled enamel in Texas. J Am Dent Assoc 108:56-59.[Medline] [Order article via Infotrieve]
  • Shinoda H. (1983). Effects of long-term administration of fluoride on the enamel formation in rats. In: Mechanisms of tooth enamel formation. Suga S, editor. Tokyo, Japan: Quintessence Publishing Co. Inc., pp. 273-284.
  • Smith CE, McKee MD, Nanci A. (1987). Cyclic induction and rapid movement of sequential waves of new smooth-ended ameloblast modulation bands in rat incisors as visualized by polychrome fluorescent labeling and GBHA staining of maturing enamel. Adv Dent Res 1:162-175.[Abstract/Free Full Text]
  • Smith CE, Nanci A., DenBesten PK (1993). Effects of chronic fluoride exposure on morphometric parameters defining the stages of amelogenesis and ameloblast modulation in rat incisors. Anat Rec 237:243-258.[CrossRef][Medline] [Order article via Infotrieve]
  • Suga S. ( 1982). Progressive mineralization pattern of developing enamel during the maturation stage. J Dent Res 61(Spec Iss):1532-1542:
  • Sydney-Zax M., Mayer I., Deutsch D. (1991). Carbonate content in developing human and bovine enamel. J Dent Res 70:913-916. Szpunar SM, Burt BA (1988). Dental caries, fluorosis, and fluoride exposure in Michigan schoolchildren. J Dent Res 67:802-806.
  • Takano Y., Crenshaw MA, Bawden JW, Hammarstrom L. (1982). The visualization of patterns of ameloblast modulation by glyoxal bis (2-hydroxyanil) staining method. J Dent Res 61(Spec Iss):1580-1586.
  • US Public Health Service (1991). Review of fluoride benefits and risks. Report of the Ad Hoc Subcommittee on Fluoride. Washington, DC: US Government Printing Office. Varughese K., Moreno EC (1981). Crystal growth of calcium
  • Weatherell JA, Deutsch D., Robinson C., Hallsworth AS (1975). Fluoride concentrations in developing enamel. Nature 256:230-232.[CrossRef][Medline] [Order article via Infotrieve]
  • Weatherell JA, Robinson C., Deutsch D. (1982). Mechanism of fluoride action and fluorosis. Fluoride 15:64-69. Yanagisawa T., Takuma S., Fejerskov O. (1989). Ultrastructure and composition of enamel in human dental fluorosis. Adv Dent Res 3:203-210.[Abstract/Free Full Text]

Journal of Dental Research, Vol. 74, No. 7, 1349-1352 (1995)
DOI: 10.1177/00220345950740070501


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
CROBMHome page
L. Li
THE BIOCHEMISTRY AND PHYSIOLOGY OF METALLIC FLUORIDE: ACTION, MECHANISM, AND IMPLICATIONS
Critical Reviews in Oral Biology & Medicine, March 1, 2003; 14(2): 100 - 114.
[Abstract] [Full Text] [PDF]


Home page
CROBMHome page
T. Aoba and O. Fejerskov
DENTAL FLUOROSIS: CHEMISTRY AND BIOLOGY
Critical Reviews in Oral Biology & Medicine, March 1, 2002; 13(2): 155 - 170.
[Abstract] [Full Text] [PDF]


Home page
ADRHome page
K.S. Prostak and Z. Skobe
Anion Translocation Through the Enamel Organ
Advances in Dental Research, November 1, 1996; 10(2): 238 - 244.
[Abstract] [PDF]


This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Bawden, J.W.
Right arrow Articles by LeGeros, R.Z.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bawden, J.W.
Right arrow Articles by LeGeros, R.Z.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?