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Effect of Hydrostatic Pressure on the Diffusion of Monomers through Dentin in vitro
T.M. Gerzina
Department of Restorative Dentistry, University of California, San Francisco, 707 Parnassus Ave., San Francisco, California 94143-0758
W.R. Hume
Department of Restorative Dentistry, University of California, San Francisco, 707 Parnassus Ave., San Francisco, California 94143-0758
In previous work, the diffusion of monomers from composite and bonding resins through dentin was demonstrated in vitro. The monomers triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA) were identified in samples from the pulp space. In the current study, we examined the effects of two levels of positive hydrostatic pressure on the passage of resin monomers through dentin in vitro from a compositeresin/bonding-resin combination to test the hypothesis that monomer diffusion is prevented by such pressure. An occlusal cavity prepared in the tooth crown was restored with the resins. Distilled water samples from the pulpal space were removed over time and analyzed for monomer content by high-performance liquid chromatography and mass spectrometry. Positive pulpal pressure reduced but did not prevent pulpward movement of diluent monomers that leach from bonding agents and from resin composites through dentin in vitro. The degree of reduction of diffusion was greater with TEGDMA than with the lower-molecular-weight monomer HEMA.
Key Words: resin monomers • hydrostatic pressure • diffusion • dentin.
REFERENCES
- Andrews SA, Van Hassell HJ, Brown AC (1972). A method for determining the physiologic basis of pulp sensory response-a preliminary report. J Hosp Dent Pract 6:49-53.[Medline]
[Order article via Infotrieve]
- Gerzina TM, Hume WR ( 1994). Effect of dentine on release of TEGDMA from resin composite in vitro. J Oral Rehabil 21:463-468.[CrossRef][Medline]
[Order article via Infotrieve]
- Heyeraas KJ (1989). Pulpal hemodynamics and interstitial fluid pressure: balance of transmicrovascular fluid transport. J Endo 15:468-472.
- Hume WR ( 1985). A new technique for screening chemical toxicity to the pulp from dental restorative materials and procedures. J Dent Res 64:1322-1325.
- Hume WR, Gerzina TM (1994). Release of monomers from bonding resin-composite resin combinations through dentin in vitro (ABSTRACT). J Dent Res 73:224.
- Maita E., Simpson MD, Tao L., Pashley DH (1991). Fluid and protein flux across the pulpodentine complex of the dog in vivo. Arch Oral Biol 36:103-110.[Medline]
[Order article via Infotrieve]
- Pashley DH (1988). Consideration of dentine permeability in cytotoxicity testing. Int Endo J 21:143-154.
- Pashley DH, Livingston MJ (1978). Effect of molecular size on permeability coefficients in human dentine. Arch Oral Biol 23:391-395.[Medline]
[Order article via Infotrieve]
- Pashley DH, Matthews WG (1993). The effects of outward forced convective flow on inward diffusion in human dentine in vitro. Arch Oral Biol 38:577-582.[CrossRef][Medline]
[Order article via Infotrieve]
- Pashley DH, Kehl T., Pashley EL, Palmer P. (1981). Comparison of in vitro and in vivo dentin permeability. J Dent Res 60:763-768.
- Ruyter JE, Sjøvik JJ (1981). Composition of dental resin and composite materials. Acta Odontol Scand 39:133-146.
- Tender KJ, Kvinnsland I. (1983). Micropuncture measurements of interstitial fluid pressure in normal and inflamed dental pulp in cats. J Endo 9:105-109.
- Van Meerbeek B., Van Herle G., Lambrechts P., Braem M. (1992). Dentin- and enamel-bonding agents. Curr Opin Dent 2:117-127.[Medline]
[Order article via Infotrieve]
- Vongsavan N., Matthews B. (1991). The permeability of cat dentine in vivo and in vitro. Arch Oral Biol 36:641-646.[Medline]
[Order article via Infotrieve]
- Vongsavan N., Matthews B. (1992). Fluid flow through cat dentine in vivo. Arch Oral Biol 37:175-185.[Medline]
[Order article via Infotrieve]
Journal of Dental Research, Vol. 74, No. 1,
369-373 (1995)
DOI: 10.1177/00220345950740011301
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