This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Skobe, Z. Articles by Stern, D.N. Search for Related Content PubMed PubMed Citation Articles by Skobe, Z. Articles by Stern, D.N. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB SODIUM FLUORIDE Social Bookmarking                         What's this?

Comparison of Rates of Enamel Synthesis in Impeded and Unimpeded Rat Incisors

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

J.D. Heeley

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

J.M. Dobeck

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

K.S. Prostak

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

L. Maravelis

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

D.N. Stern

Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115

Periodic intubations of rats with solutions of fluoride (F) lead to the appearance of bands of disrupted pigmentation in continuously erupting incisors. Distances between fluorotic bands reflect time intervals between intubations. In this experiment, the periodicity of fluorotic banding was used for estimation of the rate of enamel synthesis in impeded and unimpeded rat incisors. Rats kept on a low-F diet and distilled water were intubated two or four times per week with 2 mg NaF/150 g body weight. In a group of rats, one of the mandibular incisors was cut at the gingival margin after two weeks, and intubations were continued for an additional two weeks. In another group of F-intubated rats, incisors were cut or notched at the gingival margin twice, six days apart. Control rats either received the same periodic F intubations or were maintained on the low-F diet without intubation.

Measurements of spacing between fluorotic bands were identical in impeded and unimpeded teeth, even though the latter erupted at a faster rate. In unimpeded mandibular incisors, there was a significant elongation of the secretory zone and a shortening of the pigmentation zone, resulting in reduced pigmentation intensity of the erupted portions of the teeth. The results show that the rate of enamel synthesis is independent of the eruption rate.

REFERENCES

• Angmar-Månsson B., Whitford GM (1985). Single fluoride doses and enamel fluorosis in the rat. Caries Res 19:145-52.[Medline] [Order article via Infotrieve]
• Berkovitz Bkb (1974). Effect of fluoride on eruption rates of rat incisors. J Dent Res 53:334-337.[Abstract/Free Full Text]
• Berkovitz Bkb, Thomas NR (1969). Unimpeded eruption in the root-resected lower incisor of the rat with a preliminary note on tooth transection. Arch Oral Biol 14:771-780.[CrossRef][Medline] [Order article via Infotrieve]
• Bryer LW (1957). Physiology of tooth eruption. Int Dent J 7:432-478.
• McKee MD, Warshawsky H. (1984). In vivo experimentation on rat incisor enamel organs through a surgical window. Anat Rec 210:693-705.[CrossRef][Medline] [Order article via Infotrieve]
• Michaeli Y., Weinreb MM (1968). Role of attrition and occlusal contact in the physiology of the rat incisor: II. Diurnal rhythm in eruption and attrition. J Dent Res 47:486-491.[Abstract/Free Full Text]
• Risnes S. (1979). A method of calculating the speed of movement of ameloblasts during rat incisor amelogenesis. Arch Oral Biol 24:299-306.[CrossRef][Medline] [Order article via Infotrieve]
• Robinson C., Kirkham J., Nutman CA (1988). Relationship between enamel formation and eruption rate in rat mandibular incisors. Cell Tissue Res 254:655-658.[Medline] [Order article via Infotrieve]
• Schour I., Hoffman MM (1939). Studies in tooth development. II. The rate of apposition of enamel and dentin in man and other mammals. J Dent Res 18:161-175.[Free Full Text]
• Schour I., Smith MC (1934). The histologic changes in the enamel and dentin of the rat incisor in acute and chronic experimental fluorosis. Univ AZ Agr Exper Sta Tech Bull 52:69-91.
• Skobe Z., Heeley JD, Kashket S., Dobeck JM, LaFrazia FT, Prostak KS (1984). Banding of rat incisor enamel following pulsed ingestion of fluoride. In: Fearnhead RW, Suga S, editors. Tooth enamel IV. Amsterdam (The Netherlands): Elsevier Science Publishers, 276-280.
• Smith CE, Warshawsky H. (1975). Cellular renewal in the enamel organ and the odontoblast layer of the rat incisor as followed by radioautography using 3H- thymidine. Anat Rec 183:523-562.[CrossRef][Medline] [Order article via Infotrieve]
• Steigman S., Michaeli Y., Yitzhaki M., Weinreb M. (1974). A three-dimensional evaluation of the effects of functional occlusal forces on the morphology of dental and periodontal tissues of the rat incisor. J Dent Res 68:1269-1274.
• Warshawsky H., Smith CE (1971). A three-dimensional reconstruction of rods in rat maxillary incisor enamel. Anat Rec 169:585-592.[CrossRef][Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 72, No. 1, 46-50 (1993)
DOI: 10.1177/00220345930720010601


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				S. Risnes, C.B. Moinichen, D. Septier, and M. Goldberg Effects of Accelerated Eruption On the Enamel of the Rat Lower Incisor Advances in Dental Research, November 1, 1996; 10(2): 261 - 269. [Abstract] [PDF]

This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Skobe, Z. Articles by Stern, D.N. Search for Related Content PubMed PubMed Citation Articles by Skobe, Z. Articles by Stern, D.N. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB SODIUM FLUORIDE Social Bookmarking                         What's this?