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Effects of Fluoride and Chlorhexidine on the Microflora of Dental Root Surfaces and Progression of Root-surface Caries

Institute of Preventive and Community Dentistry, University of Nijmegen, p/o Box 9101, 6500 HB Nijmegen, The Netherlands

H.M.A.M. Keltjens

Department of Oral Function and Prosthetic Dentistry, University of Nijmegen, p/o Box 9101, 6500 HB Nijmegen, The Netherlands

J.S. Van Der Hoeven

Institute of Preventive and Community Dentistry, University of Nijmegen, p/o Box 9101, 6500 HB Nijmegen, The Netherlands

The effects of fluoride and chlorhexidine varnishes on the microflora of dental root surfaces and on the progression of root-surface caries were studied. Forty-four patients, surgically treated for advanced periodontal disease, were distributed at random among three groups. All patients received a standardized preventive treatment. Furthermore, the dentition of the patients in the two experimental groups was treated, at three-month intervals, with chlorhexidine and fluoride varnish, respectively. Patients in the control group received no additional treatment.

In the experimental groups, plaque samples were collected from selected sound and carious root surfaces at baseline and at three, six, and nine months after the onset of the study. The presence of root-surface caries was scored at baseline and after one year. In addition, the texture, depth, and color of the root-surface lesions were monitored.

Mutans streptococci on root surfaces were suppressed significantly (p<0.05) during the whole experimental period in the chlorhexidine varnish group, but not in the fluoride varnish group. A non-significant increase in the number of Actinomyces viscosus/naeslundii was noted after treatment with chlorhexidine and fluoride varnish.

The increase in the number of decayed and filled root surfaces after one year was significantly lower in the experimental groups than in the control group. After treatment with chlorhexidine varnish, significantly more initial root-surface lesions had hardened than in the other groups.

REFERENCES

• Banting, D.W.; Ellen, R.P.; and Fillery, E.D. (1985): A Longitudinal Study of Root Caries: Baseline and Incidence Data, J Dent Res 64:1141-1144.[Abstract/Free Full Text]
• Billings, R.J.; Brown, L.R.; and Kaster, A.G. (1985): Contemporary Treatment Strategies for Root Surface Dental Caries, Gerodontics 1:20-27.[Medline] [Order article via Infotrieve]
• Bowden, G.H.W. (1990): Microbiology of Root Surface Caries in Humans, J Dent Res 69:1205-1210.[Abstract/Free Full Text]
• Brown, L.R.; Billings, R.J.; and Kaster, A.G. (1986): Quantitative Comparisons of Potentially Cariogenic Microorganisms Cultured from Noncarious and Carious Root and Coronal Tooth Surfaces, Infect Immun 51:765-770.[Abstract/Free Full Text]
• Burt, B.A.; Ismail, A.I.; and Eklund, S.A. (1986): Root Caries in an Optimally Fluoridated and a High-fluoride Community, J Dent Res 65:1154-1158.[Abstract/Free Full Text]
• Ellen, R.P. and Balcerzak-Raczkowski, I.B. (1975): Differential Medium for Detecting Dental Plaque Bacteria Resembling Actinomyces viscosus and Actinomyces naeslundii, J Clin Microbiol 2:305-310.[Abstract/Free Full Text]
• Ellen, R.P.; Banting, D.W.; and Fillery, E.D. (1985a): Streptococcus mutans and Lactobacillus Detection in the Assessment of Dental Root Surface Caries Risk, J Dent Res 64:1245-1249.[Abstract/Free Full Text]
• Ellen, R.P.; Banting, D.W.; and Fillery, E.D. (1985b): Longitudinal Microbiological Investigation of a Hospitalized Population of Older Adults with a High Root Surface Caries Risk, J Dent Res 64:1377-1381.[Abstract/Free Full Text]
• Emilson, C.-G. (1977): Susceptibility of Various Microorganisms to Chlorhexidine, Scand J Dent Res 85:255-265.[Medline] [Order article via Infotrieve]
• Emilson, C.-G.; Klock, B.; and Sanford, C.B. (1988): Microbial Flora Associated with Presence of Root Surface Caries in Periodontally Treated Patients, Scand J Dent Res 96:40-49.[Medline] [Order article via Infotrieve]
• Fure, S.; Romaniec, M.; Emilson, C.G.; and Krasse, B. (1987): Proportions of Streptococcus mutans, Lactobacilli and Actinomyces spp. in Root Surface Plaque, Scand J Dent Res 95:119-123.[Medline] [Order article via Infotrieve]
• Gisselsson, H.; Birkhed, D.; and Bjorn, A.-L. (1988): Effect of Professional Flossing with Chlorhexidine Gel on Approximal Caries in 12- to 15-Year-Old Schoolchildren, Caries Res 22:187-192.[Medline] [Order article via Infotrieve]
• Hand, J.S.; Hunt, R.J.; and Beck, J.D. (1988): Coronal and Root Caries in Older Iowans: 36-Month Incidence, Gerodontics 4:136-139.[Medline] [Order article via Infotrieve]
• Hunt, R.J.; Eldredge, J.B.; and Beck, J.D. (1989): Effect of Residence in a Fluoridated Community on the Incidence of Coronal and Root Caries in an Older Adult Population, J Public Health Dent 49:138-141.[CrossRef][Medline] [Order article via Infotrieve]
• Jordan, H.V. and Hammond, B.F. (1972): Filamentous Bacteria Isolated from Human Root Surface Caries, Arch Oral Biol 17:1333-1342.[CrossRef][Medline] [Order article via Infotrieve]
• Katz, R.V.; Hazen, S.P.; Chilton, N.W.; and Mumma, R.D. (1982): Prevalence and Intraoral Distribution of Root Caries in an Adult Population, Caries Res 16:265-271.[Medline] [Order article via Infotrieve]
• Keltjens, H.M.A.M.; Schaeken, M.J.M.; Van Der Hoeven, J.S.; and Hendriks, J.C.M. (1987): Microflora of Plaque from Sound and Carious Root Surfaces, Caries Res 21:193-199.[Medline] [Order article via Infotrieve]
• Keltjens, H.M.A.M.; Schaeken, M.J.M.; Van Der Hoeven, J.S.; and Hendriks, J.C.M. (1988): Epidemiology of Root Surface Caries in Patients Treated for Periodontal Diseases, Commun Dent Oral Epidemiol 16:171-174.[CrossRef][Medline] [Order article via Infotrieve]
• Kilian, M.; Mikkelsen, L.; and Henrichsen, J. (1989): Taxonomic Study of Viridans Streptococci: Description of Streptococcus gordonii sp. nov. and Emended Descriptions of Streptococcus sanguis (White and Niven, 1946), Streptococcus oralis (Bridge and Sneath, 1982), and Streptococcus mitis (Andrewes and Horder, 1906), Int J Syst Bacteriol 39:471-484.[Abstract/Free Full Text]
• Leske, G.S. and Ripa, L.W. (1989): Three-year Root Caries Increments: Implications for Clinical Trials, J Public Health Dent 49:142-146.[CrossRef][Medline] [Order article via Infotrieve]
• Lindquist, B.; Edward, S.; Torell, P.; and Krasse, B. (1989): Effect of Different Caries Preventive Measures in Children Highly Infected with Mutans Streptococci, Scand J Dent Res 97:330-337.[Medline] [Order article via Infotrieve]
• Locker, D.; Slade, G.D.; and Leake, J.L. (1989): Prevalence of and Factors Associated with Root Decay in Older Adults in Canada, J Dent Res 68:768-772.[Abstract/Free Full Text]
• Loesche, W.J.; Hockett, R.N.; and Syed, S.A. (1972): The Predominant Cultivable Flora of Tooth Surfaces Plaque Removed from Institutionalized Subjects, Arch Oral Biol 17:1311-1326.[CrossRef][Medline] [Order article via Infotrieve]
• Markitziu, A.; Rajstein, J.; Deutsch, D.; Rahamim, E.; and Geda-Lia, I. (1988): Arrest of Incipient Cervical Caries by Topical Chemotherapy, Gerodontics 4:293-298.[Medline] [Order article via Infotrieve]
• McDermid, A.S.; McKee, A.S.; and Marsh, P.D. (1987): A Mixed-culture Chemostat System to Predict the Effect of Antimicrobial Agents on the Oral Microflora: Preliminary Studies Using Chlorhexidine, Dent Res 66:1315-1320.
• Nyvad, B. and Fejerskov, O. (1986): Active Root Surface Caries Converted into Inactive Caries as a Response to Oral Hygiene, Scand J Dent Res 94:281-284.[Medline] [Order article via Infotrieve]
• Ravald, N. and Hamp, S.-E. (1981): Prediction of Root Surface Caries in Patients Treated for Advanced Periodontal Disease, J Clin Periodontol 8:400-414.[CrossRef][Medline] [Order article via Infotrieve]
• Ravald, N.; Hamp, S.-E.; and Birkhed, D. (1986): Long-term Evaluation of Root Surface Caries in Periodontally Treated Patients, J Clin Periodontol 13:758-767.[CrossRef][Medline] [Order article via Infotrieve]
• Ripa, L.W.; Leske, G.S.; Forte, F.; and Varma, A. (1987): Effect of a 0.05% Neutral NaF Mouthrinse on Coronal and Root Caries in Adults, Gerodontology 6:131-136.[CrossRef][Medline] [Order article via Infotrieve]
• Sandham, H.J.; Brown, J.; Phillips, H.I.; and Chan, K.H. (1988): A Preliminary Report of Long-term Elimination of Detectable Mutans Streptococci in Man, J Dent Res 67:9-14.[Abstract/Free Full Text]
• Schaeken, M.J.M. and De Haan, P. (1989): Effects of Sustained-release Chlorhexidine Acetate on the Human Dental Plaque Flora, J Dent Res 68:119-123.[Abstract/Free Full Text]
• Schaeken, M.J.M.; Van Der Hoeven, J.S.; and Franken, H.C.M. (1986): Comparative Recovery of Streptococcus mutans on Five Isolation Media, Including a New Simple Selective Medium, J Dent Res 65:906-908.[Abstract/Free Full Text]
• Schaeken, M.J.M.; Van Der Hoeven, J.S.; and Hendriks, J.C.M. (1989): Effects of Varnishes Containing Chlorhexidine on the Human Dental Plaque Flora, J Dent Res 68:1786-1789.[Abstract/Free Full Text]
• Siegel, S. (1956): Nonparametric Statistics, Tokyo: McGraw-Hill Kogakusha, pp. 63-67.
• Syed, S.A.; Loesche, W.J.; Pape, H.L., Jr.; and Grenier, E. (1975): Predominant Cultivable Flora Isolated from Human Root Surface Caries Plaque, Infect Immun 11:727-731.[Abstract/Free Full Text]
• Van Der Hoeven, J.S. and Rogers, A.H. (1979): Factors Affecting the Stability of the Resident Dental Plaque Microflora of Specific Pathogen-free Rats in Relation to the Ability to Resist Colonization by Streptococcus mutans, Arch Oral Biol 24:787-790.[CrossRef][Medline] [Order article via Infotrieve]
• Vehkalahti, M.M. and Paunio, I.K. (1988): Occurrence of Root Caries in Relation to Dental Health Behavior, J Dent Res 67:911-914.[Abstract/Free Full Text]
• Zickert, I.; Emilson, C.G.; and Krasse, B. (1982): Effect of Caries Preventive Measures in Children Highly Infected with the Bacterium Streptococcus mutans, Arch Oral Biol 27:861-868.[CrossRef][Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 70, No. 2, 150-153 (1991)
DOI: 10.1177/00220345910700021101


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