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Root Hard-tissue Demineralization Rate Measured by 125I Absorptiometry: Comparison with Lesion-depth Measurements
H. Almqvist
Department of Cariology, Karolinska Institutet, School of Dentistry, Box 4064, 141 04 Huddinge, Sweden
J.S. Wefel
Specialized Caries Research Center, College of Dentistry, The University of Iowa, Iowa City, Iowa 52242
F. Lagerlof
Department of Cariology, Karolinska Institutet, School of Dentistry, Box 4064, 141 04 Huddinge, Sweden
The aim of the present study was to compare demineralization of root hard tissue, monitored by 125 I absorptiometry, with lesion-depth measurements under polarized light microscopy. The intact roots of ten human molars, which had not been exposed to the oral environment, were divided into 39 cementum/dentin blocks and exposed to a buffer solution of pH 4.5 containing 2.2 mmol/L calcium and inorganic phosphate. After demineralization for 3.5, 7, 14, and 21 days, transmission measurements by 125I absorptiometry were performed, and one block from each tooth was taken out of the solution for lesion-depth measurement. The results showed a high degree of correlation (r = 0.952) between lesion depth and change in transmission, with a more rapid increase initially in both variables. A linear relationship with the square root of time was found. Conversion of transmission data to lesion-depth data was possible when this caries model system was used on cementum/ dentin blocks.
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Journal of Dental Research, Vol. 69, No. 8,
1519-1521 (1990)
DOI: 10.1177/00220345900690081401

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H. Almqvist and F. Lagerlof
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December 1, 1993;
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