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Assessment of Loosely-bound and Firmly-bound Fluoride Uptake by Tooth Enamel from Topically Applied Fluoride Treatments

American Dental Association Health Foundation, Paffenbarger Research Center, National Institute of Standards and Technology, Gaithersburg, Maryland 20899

S. Takagi

American Dental Association Health Foundation, Paffenbarger Research Center, National Institute of Standards and Technology, Gaithersburg, Maryland 20899

L.C. Chow

American Dental Association Health Foundation, Paffenbarger Research Center, National Institute of Standards and Technology, Gaithersburg, Maryland 20899

The amounts of loosely-bound fluoride (F) deposited on human enamel by two topical F treatments were measured with use of a constant-composition F washing method. Enamel biopsies conducted before treatment and after the washing were used for determination of the firmly-bound F uptake. The results showed that (1) the washing system did not remove F from untreated enamel surface, (2) a four-minute application of an acidulated phosphate fluoride (APF) gel deposited 27.2 (2.4) (mean, S.E.) µg of loosely-bound Fper cm2 of enamel surface and 186 (111) ppm of firmly-bound F in the outer 10 µm of enamel, and (3) a four-minute application of a pH-2.1 dicalcium phosphate dihydrate (DCPD)-forming solution followed by APF produced 44.9 (3.1) µg/cm2 of loosely-bound F and 1280 (354) ppm of firmly-bound F in the outer 10 µm of enamel. The results showed that the DCPD pre-treatment effectively enhanced the enamel reactivity with F, so that the DCPD-APF treated enamel acquired greater amounts of both loosely-bound F and firmly-bound F than did samples treated with APF alone.

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Journal of Dental Research, Vol. 69, No. 6, 1261-1265 (1990)
DOI: 10.1177/00220345900690060701


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Sieck, B. Articles by Chow, L.C. Search for Related Content PubMed PubMed Citation Articles by Sieck, B. Articles by Chow, L.C. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB CALCIUM BIS(DIHYDROGEN PHOSPHATE) CALCIUM HYDROGEN PHOSPHATE SODIUM FLUORIDE Social Bookmarking                         What's this?