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Optical Quantification of Caries-like Lesions in vitro by Use of a Fluorescent Dye

Laboratory for Materia Technica, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands

J.J. Ten Bosch

Laboratory for Materia Technica, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands

An experimental method was developed for measurement of the fluorescence intensity of a dye that was introduced into caries-like lesions in vitro. A distinct pattern of change of fluorescence intensity with time appeared, displaying a plateau value and a peak value for each measurement. Both plateau and peak values showed a linear correlation with calcium loss, as measured with longitudinal microradiography. The correlation coefficients were r = 0.87 for plateau values and r = 0.89 for peak values. The difference in scattering by dry and wet caries lesions was also measured with the same equipment, which showed a linear correlation with calcium loss of r = -0.53.

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Journal of Dental Research, Vol. 69, No. 5, 1184-1187 (1990)
DOI: 10.1177/00220345900690051201


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This article has been cited by other articles:

				J.J. Ten Bosch and B. Angmar-Mansson Invited Review: A Review of Quantitative Methods for Studies of Mineral Content of Intra-oral Incipient Caries Lesions Journal of Dental Research, January 1, 1991; 70(1): 2 - 14. [Abstract] [PDF]

This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Van de Rijke, J.W. Articles by Ten Bosch, J.J. Search for Related Content PubMed PubMed Citation Articles by Van de Rijke, J.W. Articles by Ten Bosch, J.J. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB CALCIUM COMPOUNDS CALCIUM, ELEMENTAL Social Bookmarking                         What's this?