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A Comparison of the Influence of Lanthanum and Fluoride on De- and Remineralization of Bovine Enamel in vitro

Vrije Universiteit Brussel, Faculteit Geneeskunde en Farmacie, PRTA, Laarbeeklaan 103, B-1090 Brussels, Belgium

D. Slop

Vrije Universiteit Brussel, Faculteit Geneeskunde en Farmacie, PRTA, Laarbeeklaan 103, B-1090 Brussels, Belgium

L. De Langhe

Vrije Universiteit Brussel, Faculteit Geneeskunde en Farmacie, PRTA, Laarbeeklaan 103, B-1090 Brussels, Belgium

D. Coomans

Vrije Universiteit Brussel, Faculteit Geneeskunde en Farmacie, PRTA, Laarbeeklaan 103, B-1090 Brussels, Belgium

The influence of fluoride and lanthanum on enamel softening was compared by hardness measurements and by determination of the calcium content in the solution. The addition of lanthanum to an acetate buffer solution (0.05 mollL, pH=5.0) had no significant influence on the change of the indentation length and on the calcium release, compared with those of the control group. In the fluoride group, a moderate increase of the indentation length and a reduced calcium loss were observed. In a second experiment, surface-softened bovine enamel was treated with calcifying solutions (Ca/P ratio = 1. 67). Differences in treatment were created by the addition of traces (2 ppm) of lanthanum, fluoride, or both. The acid resistance of the treated enamel was evaluated by two successive softening steps (0.1 mol/L acetate buffer, pH = 5.5). Alterations of the enamel surface were longitudinally followed with a hardness tester. The addition of fluoride, lanthanum, or both significantly improved the rehardening of surface-softened enamel, compared with that of the control group. A 2 x 2 factorial analysis of variance showed that lanthanum and fluoride had a highly significant main effect and a significant negative interaction effect on the rehardening of surface-softened enamel. Subsequent acid treatments revealed that only samples treated with a fluoride-containing solution were adequately protected from further dissolution. The enamel surfaces treated with a solution containing both lanthanum and fluoride were covered with an acid-resistant surface coating. SEM observation of this surface layer revealed the presence of globular and spherulite structures.

REFERENCES

• Boddé, H.E.; Nelson, D.G.A.; Koops, P.G.; and Arends, J. (1985): Influence of Repeated APF Applications on Long-term Remineralization of Initial Lesions in Bovine Enamel, J Dent Res 64:12-18.[Free Full Text]
• Brudevold, F.; Tehrani, A.; Attarzadeh, D.; Goulet, D.; and Van Houte, J. (1985): Effect of Some Salts of Calcium, Sodium, Potassium, and Strontium on Intra-oral Enamel Demineralization, J Dent Res 64:24-27.[Abstract/Free Full Text]
• Clarkson, B.H.; Wefel, J.S.; Miller, I.; and Edie, J. (1984): Microprobe and SEM Analysis of Surface Coatings on Caries-like Lesions in Enamel after Metal Ion Mordanting and APF Application, J Dent Res 63:106-110.[Abstract/Free Full Text]
• Collys, K.; Slop, D.; and Coomans, D. (1988): The Influence of Trace-elements on the De- and Remineralization Properties of Tooth Enamel in vitro, Trace Elements in Medicine 5:161-169.
• Collys, K.; Quartier, E.; Slop, D.; and Coomans, D. (1989): The Fluoride Uptake by Softened Bovine Enamel in the Presence of Lanthanum, J Dent Res 68:617, Abst. No. 69.
• Gelhard, T.B.F.M. (1982): Remineralization of Human Enamel in vivo, Ph.D. Thesis, Groningen, pp. 27-54.
• Grøn, P. (1977): Chemistry of Topical Fluorides, Caries Res 11 (Suppl. 1):172-204.[Medline] [Order article via Infotrieve]
• Howell, D.C. (1987): Factorial Analysis of Variance. In: Statistical Methods for Psychology, Boston: Duxbury Press, pp. 360-412.
• Kobayashi, Y.; Ozeki, M.; Takei, M.; and Shimano, R. (1979a): Influence of Lanthanum on Oral Microbes, J Dent Health (Tokyo) 29:2-9.
• Kobayashi, Y.; Ozeki, M.; Takei, M.; and Shimano, R. (1979b): Absorption of Lanthanum by the Enamel Surface of Extracted Human Teeth, J Dent Health ( Tokyo) 29:276-290.
• Kobayashi, Y.; Ozeki, M.; Yagi, T.; Hosoi, T.; and Takei, M. (1980a): X-Ray Diffraction Analysis of the Reaction Products of Hydroxyapatite and Lanthanum, J Dent Health ( Tokyo) 29:354-360.
• Kobayashi, Y.; Ozeki, M.; Yagi, T.; Hosoi, T.; and Takei, M. (1980b): Aciduric Resistance of Lanthanum-treated Teeth, J Dent Health (Tokyo) 30:388-402.
• Luoma, A.R.; Luoma, H.; Raisanen, J.; and Hausen, H. (1983): Effect of Magnesium and Fluoride on the Fermentative Dissolution of Enamel by a Streptococcal Layer as Measured by Microhardness Tester and a Proton Probe Microanalysis, Caries Res 17:430-438.[Medline] [Order article via Infotrieve]
• Nelson, D.G.A.; Jongebloed, W.L.; and Arends, J. (1983): Morphology of Enamel Surfaces Treated with Topical Fluoride Agents: SEM Considerations, J Dent Res 62:1201-1208.[Abstract/Free Full Text]
• Ozeki, M. (1982): Relative Changes of the Oral Microflora in the Induction and the Lanthanum Inhibition of Dental Caries in Rats, Aichi-Gakuin J Dent Sci 19:364-398.
• Ozeki, M.; Kobayashi, Y.; Takei, M.; and Shimano, R. (1979): Inhibition of Dental Caries by Lanthanum, J Dent Health (Tokyo) 28:448-454.
• Sakurai, Y. (1982): Distribution and Fate of Lanthanum in the Tissues of Rats Administered Lanthanum Salt Solution-by means of Swabbing the Solutions on the Teeth and through Stomach Tube, Aichi-Gakuin J Dent Sci 20:1-17.
• Shimano, R. (1980): A Fundamental Study on Lanthanum as a Preventive of Dental Caries, J Dent Health (Tokyo ) 29:361-377.
• Ten Cate, J.M. and Duijsters, P.P.F. (1982): Alternating Demineralization and Remineralization of Artificial Enamel Lesions, Caries Res 16:201-210.[Medline] [Order article via Infotrieve]
• Winter, M.R.C.; Rolla, G.; and White, A.J. (1980): The Effects of Inorganic Cations on Dental Plaque. In: Dental Plaque and Surface Interactions in the Oral Cavity, S.A. Leach, Ed., London: IRL Press, pp. 211-223.

Journal of Dental Research, Vol. 69, No. 2, 458-462 (1990)
DOI: 10.1177/00220345900690020801


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