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Analysis of Particle Size Distribution of Hydroxyapatite Crystallites in the Presence of Synthetic and Natural Polymers

Department of Chemistry, State University of New York at Buffalo, Buffalo, New York 14214

J.A. Budz

Eastman Kodak Company, Kodak Park, Rochester, New York 14650

The particle size distribution (PSD) of suspended hydroxyapatite crystallites both at equilibrium and during crystal growth has been measured by a laser scattering technique. Addition of high-molecular-weight polyacrylate (PAA/C) resulted in appreciable crystallite aggregation, probably by polymer bridging of particles. In contrast, a lower-molecular-weight PAA was unable to bridge the hydrodynamic gap between particles and resulted in an overall dispersion. The addition of human serum albumin also markedly influenced the PSD and, with concomitant change in zeta potential to more negative values, resulted in dispersion due to steric interaction and electrostatic repulsion between the particles. The complex behavior of human saliva is illustrated by its tendency both to aggregate and to disperse hydroxyapatite crystallites, displaying the combined effects of different adsorbing macromolecules.

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Journal of Dental Research, Vol. 69, No. 10, 1678-1685 (1990)
DOI: 10.1177/00220345900690101001


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Nancollas, G.H. Articles by Budz, J.A. Search for Related Content PubMed PubMed Citation Articles by Nancollas, G.H. Articles by Budz, J.A. Social Bookmarking                         What's this?