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Comparative Microbiological and Immunological Studies of Subgingival Dental Plaque from Man and Baboons

Dental Research Department, U.S. Naval Medical Research Unit No. 3, Cairo, Egypt

M.O. Wasfy

Dental Research Department, U.S. Naval Medical Research Unit No. 3, Cairo, Egypt

W.P. Yonushonis

Dental Research Department, U.S. Naval Medical Research Unit No. 3, Cairo, Egypt

G.E. Minah

University of Maryland Dental School, Baltimore, Maryland

W.A. Falkler, Jr

University of Maryland Dental School, Baltimore, Maryland

Baboons may be useful as animal models for the study of human oral diseases and infections. They are closely related to man anatomically, physiologically, and phylogenetically. Plaque and gingival indices were relatively low in 18 baboons (Papio anubis). The mean scores ranged between 0.62 ± 0.29 and 0.37 ± 0.20, respectively. Gram-positive and Gram-negative cocci comprised 27.0 ± 32.4 and 3.1 ± 7.5% of the total viable counts in the dental plaque samples. Black-pigmented Bacteroides formed about 1.9 ± 5.9% of the bacterial population in the samples. Anaerobic Gram-negative bacilli were found in 73.2% of the samples and averaged 19.2 t 26.3% of the total recovered flora. Species of the oral Actinomyces and other Gram-positive rods found in humans were not isolated. The composition of the oral flora in baboons appeared to be significantly different from that of man. Isolates of F. nucleatum, L. buccalis, and B. intermedius from the two mammals were biochemically similar, but were distinguishable by analysis with antibody, both by precipitin lines and/or differences between homologous and heterologous titers.

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Journal of Dental Research, Vol. 69, No. 1, 55-59 (1990)
DOI: 10.1177/00220345900690010901


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by McMahon, K.T. Articles by Falkler, W.A. Search for Related Content PubMed PubMed Citation Articles by McMahon, K.T. Articles by Falkler, W.A., Jr Social Bookmarking                         What's this?