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Role of Parotid Amylase in Starch Digestion in the Gastro-intestinal Tracts of Diabetic Rats

Department of Oral Physiology, School of Dentistry, Higashi-Nippon-Gakuen University, Ishikari-Tobetsu, Hokkaido, 061-02, Japan

K. Inomata

Department of Oral Physiology, School of Dentistry, Higashi-Nippon-Gakuen University, Ishikari-Tobetsu, Hokkaido, 061-02, Japan

In order for the role of parotid amylase in starch digestion in the gastro-intestinal tracts of diabetic rats to be clarified, this study investigated the effect of parotid-duct ligation on both amylase secretion from the parotid glands and pancreas into the gastro-intestinal tract and on starch digestion in the gastro-intestinal contents during feeding. In both diabetic rats and control rats, parotid-duct ligation reduced amylase activity in both the parotid glands during fasting and in the gastric contents after feeding. The amylase activity in the intestinal contents after feeding was reduced by parotid-duct ligation in the diabetic rats. Starch digestion in the gastro-intestinal tract after feeding was reduced by parotid-duct ligation in the diabetic rats. The results suggest that most of the amylase activity in the gastric contents and a large part of the amylase activity in the intestinal contents are derived from the parotid glands, and that parotid amylase plays an important role in starch digestion in the gastro-intestinal tracts of diabetic rats.

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Journal of Dental Research, Vol. 68, No. 9, 1366-1369 (1989)
DOI: 10.1177/00220345890680091501


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Kurahashi, M. Articles by Inomata, K. Search for Related Content PubMed PubMed Citation Articles by Kurahashi, M. Articles by Inomata, K. Social Bookmarking                         What's this?