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The Modified Model Cavity Method for Assessing Antibacterial Properties of Dental Restorative Materials

Department of Oral Pathology, The Dental School, St. Chad's Queensway, Birmingham B4 6NN, United Kingdom

S.G. Johnson

Department of Oral Pathology, The Dental School, St. Chad's Queensway, Birmingham B4 6NN, United Kingdom

A new in vitro method for assessing the antibacterial properties of dental restorative materials is described with ratios of test material/ culture medium volume aiming to simulate conditions around a restoration in vivo. Antibacterial activity is determined by the reduction in optical density of the test culture relative to controls. The method was used for assessment of the antibacterial activity of five dental materials of different composition against five oral bacteria. Release of zinc and fluoride from these materials was also measured and correlated with antibacterial activity. There was a general trend toward greater antibacterial activity with increased zinc release, while fluoride release had a significant effect on only one organism. While all the materials, when freshly mixed, were strongly toxic to three out of the five bacteria studied, much of this activity was lost after the materials had set.

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Journal of Dental Research, Vol. 68, No. 5, 835-839 (1989)
DOI: 10.1177/00220345890680051701


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Meryon, S.D. Articles by Johnson, S.G. Search for Related Content PubMed PubMed Citation Articles by Meryon, S.D. Articles by Johnson, S.G. Social Bookmarking                         What's this?