Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Journal of Dental Research
This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Tylenda, C.A.
Right arrow Articles by Baum, B.J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tylenda, C.A.
Right arrow Articles by Baum, B.J.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Evaluation of Submandibular Salivary Flow Rate in Different Age Groups

C.A. Tylenda

Clinical Investigations and Patient Care Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892

J.A. Ship

Clinical Investigations and Patient Care Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892

P.C. Fox

Clinical Investigations and Patient Care Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892

B.J. Baum

Clinical Investigations and Patient Care Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892

The production of unstimulated and citrate-stimulated submandibular saliva was examined in 90 male and female adults, aged 26-93 years. None was taking prescription medications for treatment of systemic disease. There was no diminution in submandibular gland fluid output, at rest or during stimulation, with increasing age. Similar findings, previously reported for the parotid glands, were also confirmed. These results demonstrate that major gland fluid secretion capacity is maintained in healthy older individuals.

REFERENCES

  • Aguirre, A.; Levine, M.J.; Cohen, R.E.; and Tabak, L.A. (1987): Immunochemical Quantitation of a-Amylase and Secretory IgA in Parotid Saliva from People of Various Ages, Arch Oral Biol 32:297-301.[CrossRef][Medline] [Order article via Infotrieve]
  • Andrew, W. (1952): A Comparison of Age Changes in Salivary Glands of Man and of the Rat, J Gerontol 7:178-190.[Medline] [Order article via Infotrieve]
  • Baum, B.J. (1981): Evaluation of Stimulated Parotid Saliva Flow Rate in Different Age Groups, J Dent Res 60:1292-1296.[Abstract/Free Full Text]
  • Baum, B.J.; Costa, P.T., Jr.; and Izutsu, K.T. (1984): Sodium Handling by Aging Human Parotid Glands is Inconsistent with a Two-stage Secretion Model, Am J Physiol 246:R35-R39.
  • Baum, B.J.; Kousvelari, E.E.; and Oppenheim, F.G. (1982): Exocrine Protein Secretion from Human Parotid Glands During Aging: Stable Release of the Acidic Proline-rich Proteins, J Gerontol 37:392-395.[Abstract/Free Full Text]
  • Bertram, U. (1967): Xerostomia, Acta Odontol Scand 25: Supplement 49.
  • Chauncey, H.H.; Borkan, G.; Wayler, A.; Feller, R.P.; and Kapur, K.K. (1981): Parotid Fluid Composition in Healthy Aging Males, Adv Physiol Sci 28:323-328.
  • Dawes, C. (1975): Circadian Rhythms in the Flow Rate and Composition of Unstimulated and Stimulated Human Submandibular Saliva, J Physiol Lond 244:535-548.[Abstract/Free Full Text]
  • Ferguson, D.B. and Botchway, C.A. (1979): Circadian Variations in Flow Rate and Composition of Human Stimulated Submandibular Saliva, Arch Oral Biol 24:433-437.[CrossRef][Medline] [Order article via Infotrieve]
  • Ferguson, D.B. and Fort, A. (1974): Circadian Variations in Human Resting Submandibular Saliva Flow Rate and Composition, Arch Oral Biol 19:47-55.[CrossRef][Medline] [Order article via Infotrieve]
  • Fox, P.C.; Busch, K.A.; and Baum, B.J. (1987a): Subjective Reports of Xerostomia and Objective Measures of Salivary Gland Performance, J Am Dent Assoc 115:581-584.[Abstract]
  • Fox, P.C.; Heft, M.W.; Herrera, M.; Bowers, M.R.; Mandel, I.D.; and Baum, B.J. (1987b): Secretion of Antimicrobial Proteins from the Parotid Glands of Different Aged Healthy Persons, J Gerontol 42:466-469.[Abstract/Free Full Text]
  • Fox, P.C.; Van Der Ven, P.F.; Sonies, B.C.; Weiffen-Bach, J.M.; and Baum, B.J. (1985): Xerostomia: Evaluation of a Symptom with Increasing Significance, J Am Dent Assoc 110:519-525.[Abstract]
  • Franks, A.S.T. and Hedegaard, B. (1973): Geriatric Dentistry, Oxford: Blackwell Scientific Pub.
  • Gandara, B.K.; Izutsu, K.T.; Truelove, E.L.; Ensign, W.Y.; and Sommers, E.E. (1985): Age-related Salivary Flow Rate Changes in Controls and Patients with Oral Lichen Planus, J Dent Res 63:1149-1152.
  • Goss, C.M. (1967): Gray's Anatomy, 28th ed., Philadelphia: Lea and Febiger, p. 1196.
  • Heft, M.W. and Baum, B.J. (1984): Unstimulated and Stimulated Parotid Salivary Flow Rate in Individuals of Different Ages, J Dent Res 63:1182-1186.[Abstract/Free Full Text]
  • Langer, A. (1976): Oral Signs of Aging and their Clinical Significance, Geriatrics 31:63-69.
  • Mandel, I.D. (1987): The Functions of Saliva, J Dent Res 66:623-627.[Medline] [Order article via Infotrieve]
  • Meyer, J. and Necheles, H. (1940): Studies in Old Age IV. The Clinical Significance of Salivary, Gastric and Pancreatic Secretion in the Aged , J Am Med Assoc 115:2050-2053.[Abstract/Free Full Text]
  • Pedersen, W.; Schubert, M.; Izutsu, K.T.; Mersai, T.; and Truelove, E. (1985): Age-dependent Decreases in Human Submandibular Gland Flow Rate as Measured Under Resting and Post-stimulation Conditions, J Dent Res 64:822-826.[Abstract/Free Full Text]
  • Schneyer, L.H. and Levin, L.K. (1955): Rate of Secretion by Individual Salivary Gland Pairs of Man Under Conditions of Reduced Exogenous Stimulation, J Appl Physiol 7:508-512.[Free Full Text]
  • Scott, J. (1975): Age, Sex and Contralateral Differences in the Volume of Human Submandibular Salivary Glands, Arch Oral Biol 20:885-887.[CrossRef][Medline] [Order article via Infotrieve]
  • Scott, J. (1977): Quantitative Age Changes in the Histological Structure of Human Submandibular Salivary Glands, Arch Oral Biol 22:221-227.[CrossRef][Medline] [Order article via Infotrieve]
  • Scott, J. (1979): The Proportional Volume of Mucous Acinar Cells in Normal Human Submandibular Salivary Glands, Arch Oral Biol 24:479-481.[CrossRef][Medline] [Order article via Infotrieve]
  • Scott, J. (1987): Structure and Function in Aging Human Salivary Glands, Gerodontology 5:149-158.
  • Truelove, E.L.; Bixler, D.; and Merritt, A.D. (1967): Simplified Method for Collection of Pure Submandibular Saliva in Large Volumes, J Dent Res 46:1400-1403.[Free Full Text]
  • Waterhouse, J.P.; Chisholm, D.M.; Winter, B.B.; Patel, M.; and Yale, R.S. (1973): Replacement of Functional Parenchymal Cells by Fat and Connective Tissue in Human Submandibular Salivary Glands: An Age Related Change, J Oral Pathol 2:16-27.[CrossRef][Medline] [Order article via Infotrieve]
  • Young, J.A. and Van Lennep, E.W. (1979): Salivary and Salt Glands. In: Membrane Transport in Biology, G. Giebisch, D.C. Tosteson, and H.H. Ussing, Eds., Berlin: Springer-Verlag, pp. 563-674.

Journal of Dental Research, Vol. 67, No. 9, 1225-1228 (1988)
DOI: 10.1177/00220345880670091501


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
Ann Rheum DisHome page
T. Uhlig, T. K. Kvien, J. L. Jensen, and T. Axéll
Sicca symptoms, saliva and tear production, and disease variables in 636 patients with rheumatoid arthritis
Ann Rheum Dis, July 1, 1999; 58(7): 415 - 422.
[Abstract] [Full Text]


Home page
JDRHome page
A. Wolff, A. Begleiter, and D. Moskona
A Novel System of Human Submandibular/Sublingual Saliva Collection
Journal of Dental Research, November 1, 1997; 76(11): 1782 - 1786.
[Abstract] [PDF]


Home page
JDRHome page
J.A. Ship, A. Eisbruch, E. D'Hondt, and R.E. Jones
Parotid Sparing Study in Head and Neck Cancer Patients Receiving Bilateral Radiation Therapy: One-year Results
Journal of Dental Research, March 1, 1997; 76(3): 807 - 813.
[Abstract] [PDF]


Home page
JDRHome page
D.J. Culp and L.A. Richardson
Regulation of Mucous Acinar Exocrine Secretion with Age
Journal of Dental Research, January 1, 1996; 75(1): 575 - 580.
[Abstract] [PDF]


Home page
JDRHome page
R.S. Percival, S. Challacombe, and P.D. Marsh
Flow Rates of Resting Whole and Stimulated Parotid Saliva in Relation to Age and Gender
Journal of Dental Research, August 1, 1994; 73(8): 1416 - 1420.
[Abstract] [PDF]


Home page
JDRHome page
T.O. Narhi, J.H. Meurman, A. Ainamo, J.M. Nevalainen, K.G. Schmidt-Kaunisaho, P. Siukosaari, J. Valvanne, T. Erkinjuntti, R. Tilvis, and E. Makila
Association Between Salivary Flow Rate and the Use of Systemic Medication Among 76-, 81-, and 86-year-old Inhabitants in Helsinki, Finland
Journal of Dental Research, December 1, 1992; 71(12): 1875 - 1880.
[Abstract] [PDF]


Home page
JDRHome page
M. Navazesh, R.A. Mulligan, V. Kipnis, P.A. Denny, and P.C. Denny
Comparison of Whole Saliva Flow Rates and Mucin Concentrations in Healthy Caucasian Young and Aged Adults
Journal of Dental Research, June 1, 1992; 71(6): 1275 - 1278.
[Abstract] [PDF]


Home page
CROBMHome page
B. J. Baum, J. A. Ship, and A. J. Wu
Salivary Gland Function and Aging: A Model for Studying the Interaction of Aging and Systemic Disease
Critical Reviews in Oral Biology & Medicine, January 1, 1992; 4(1): 53 - 64.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
P. C. Fox, J. C. Atkinson, A. A. Macynski, A. Wolff, D. S. Kung, I. H. Valdez, W. Jackson, R. A. Delapenha, J. Shiroky, and B. J. Baum
Pilocarpine Treatment of Salivary Gland Hypofunction and Dry Mouth (Xerostomia)
Arch Intern Med, June 1, 1991; 151(6): 1149 - 1152.
[Abstract] [PDF]


This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Tylenda, C.A.
Right arrow Articles by Baum, B.J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tylenda, C.A.
Right arrow Articles by Baum, B.J.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?