|
Sign In to gain access to subscriptions and/or personal tools.
|
Effects of Age on the Ability of the Rat Temporomandibular Joint to Respond to Changing Functional Demands
M. Bouvier
Department of Anatomy, 1100 Florida Avenue, Louisiana State University, School of Dentistiy, New Orleans, Louisiana 70119
This investigation examined the ability of the tissues of the temporomandibular joint (TMJ) to adapt to changing functional demands in young, growing rats compared with mature rats. Functional demands on the TMJ were varied by feeding diets with diffetvnt physical consistencies. The first group was fed a soft diet for the experimental period. The second group was fed a hard diet, and the third group was initially fed the soft diet, then switched to the hard diet at the mid-point of the experimental period. Gross dimensions of the condyle, mandible, and maxilla were measured with calipers. Thickness of the articular, proliferative, transitional, and hypetirophic zones of the condylar cartilage, and the amount of bone in the subcondylar region and condylar neck were measured on histological sections. Gross dimensions of the condyle were significantly smaller in the soft-diet group compared with the hard- and soft/hard-diet groups in both growing and mature rats. The individual zones of the condylar cartilage were also significantly narrower in the soft-diet group in both growing and mature rats. However, the soft/hard-diet group of mature rats showed only a significant reduction in the thickness of the articular zone of the condylar cartilage compared with the hard-diet group. There were also narrower proliferative and transitional zones in the mature rats fed a soft/hard diet. In contrast, all of these zones showed full recovery in the young rats fed a soft/hard diet. The data presented here suggest that increasing age may diminish the capacity of the TMJ to adapt to altered function and consequently may play a significant role in the development of degenerative joint disease.
REFERENCES
- Beecher, R.M. and Corruccini, R.S. (1981): Effects of Dietary Consistency on Craniofacial and Occlusal Development in the Rat, Angle Ortho 51:61-69.
- Bouvier, M. (1981): The Relationship Between in vivo Stress and Morphology in Tibial and Mandibular Bone from Several Species of Mammals. Ph.D. Dissertation, Duke University, Durham, NC, pp. 129-237.
- Bouvier, M. (1987): Variation in Alkaline-Phosphatase Activity with Changing Load on the Mandibular Condylar Cartilage in the Rat, Arch Oral Biol 32:671-676.[CrossRef][Medline]
[Order article via Infotrieve]
- Bouvier, M. and Hylander, W.L. (1982): The Effect of Dietary Consistency on Morphology of the Mandibular Condylar Cartilage in Macaques (Macaca mulatta). In: Factors and Mechanisms Influencing Bone Growth, A.D. Dixon and B.G. Sarnat, Eds., New York: Alan R. Liss, Inc., pp. 569-579.
- Bouvier, M. and Hylander, W.L. (1984): The Effect of Dietary Consistency on Gross and Histologic Morphology in the Craniofacial Region of Young Rats, Am J Anat 170:117-126.[CrossRef][Medline]
[Order article via Infotrieve]
- Bouvier, M. and Zimny, M.L. (1987): Effects of Mechanical Loads on Surface Morphology of the Condylar Cartilage of the Mandible in Rats, Acta Anat 129:292-300.
- Copray, J.C.V.M.; Jansen, H.W.B.; and Duterloo, H.S. (1985a): The Role of Biomechanical Factors in Mandibular Condylar Cartilage Growth and Remodeling in vitro. In: Developmental Aspects of Temporomandibular Joint Disorders, D.S. Carlson, J.A. McNamara, Jr., and K.A. Ribbens, Eds., Ann Arbor, Michigan: Univ. of Michigan, pp. 235-269.
- Copray, J.C.V.M.; Jansen, H.W.B.; and Duterloo, H.S. (1985b): Effects of Compressive Forces on Proliferation and Matrix Synthesis in Mandibular Condylar Cartilage of the Rat in vitro, Arch Oral Biol 30:299-304.[CrossRef][Medline]
[Order article via Infotrieve]
- Copray, J.C.V.M.; Jansen, H.W.B.; and Duterloo, H.S. (1985c): Effect of Compressive Forces on Phosphatase Activity in Mandibular Condylar Cartilage of the Rat in vitro, J Anat 140:479-489.
- Corruccini, R.S. and Beecher, R.M. (1984): Occlusofacial Morphological Integration Lowered in Baboons Raised on Soft Diet, J Craniofacial Genet 4:135-142.
- Glineburg, R.W.; Laskin, D.M.; and Blaustein, D.I. (1982): The Effects of Immobilization on the Primate Temporomandibular Joint: A Histological and Histochemical Study, J Oral Maxillofac Surg 40:3-8.[Medline]
[Order article via Infotrieve]
- Hinton, R.J. (1981): Form and Function in the Temporomandibular Joint. In: Craniofacial Biology, D.S. Carlson, Ed., Ann Arbor, Michigan: Center for Human Growth and Development, pp. 37-60.
- Hinton, R.J. and Carlson, D.S. (1986): Response of the Mandibular Joint to Loss of Incisal Function in the Rat, Acta Anat 125:145-151.[Medline]
[Order article via Infotrieve]
- Lubsen, C.C.; Hansson, T.L.; Nordstrom, B.B.; and Sol-Berg, W.K. (1987): Histomorphometry of Age and Sex Changes in Mandibular Condyles of Young Human Adults, Arch Oral Biol 32:729-733.[Medline]
[Order article via Infotrieve]
- Lydiatt, D.D. and Davis, L.F. (1985): The Effects of Immobilization on the Rabbit Temporomandibular Joint, J Oral Maxillofac Surg 43: 188-193.[Medline]
[Order article via Infotrieve]
- Petrovic, A.; Stutzmann, J.J.; and Oudet, C.L. (1975): Control Processes in the Postnatal Growth of the Condylar Cartilage of the Mandible. In: Determinants of Mandibular Form and Growth, Ann Arbor, Michigan: Center for Human Growth and Development, pp. 101-153.
- Richards, L.C.; Lau, E.; and Wilson, D.F. (1984): Histopathology of the Mandibular Condyle, J Oral Pathol 14:624-630.
- Simon, M.R. (1977): The Role of Compressive Forces in the Normal Maturation of the Condylar Cartilage, Acta Anat 97:351-360.[Medline]
[Order article via Infotrieve]
- Watt, D.G. and Williams, C.H.M. (1951): The Effects of Physical Consistency of Food on Growth and Development of the Mandible and Maxilla of the Rat, Am J Orthod 37:895-928.[CrossRef][Medline]
[Order article via Infotrieve]
- Weiss, A.; Livne, E.; Bernheim, J.; and Silbermann, M. (1986): Structural and Metabolic Changes Characterizing the Aging of Various Cartilages in Mice, Mech Aging Devel 35:145-160.
- Zarb, G.A. and Carlsson, G.E. (1979): Temporomandibular Joint Function and Dysfunction, St. Louis, Missouri: C.V. Mosby Co.
Journal of Dental Research, Vol. 67, No. 9,
1206-1212 (1988)
DOI: 10.1177/00220345880670091101
 CiteULike  Complore  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter What's this?
This article has been cited by other articles:
|
|
|
|
 
A. Enomoto, J. Watahiki, T. Yamaguchi, T. Irie, T. Tachikawa, and K. Maki
Effects of mastication on mandibular growth evaluated by microcomputed tomography
Eur J Orthod,
July 31, 2009;
(2009)
cjp060v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. J. Ravosa, E. K. Lopez, R. A. Menegaz, S. R. Stock, M. S. Stack, and M. W. Hamrick
Using "Mighty Mouse" to understand masticatory plasticity: myostatin-deficient mice and musculoskeletal function
Integr. Comp. Biol.,
September 1, 2008;
48(3):
345 - 359.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Wadhwa and S. Kapila
TMJ Disorders: Future Innovations in Diagnostics and Therapeutics
J Dent Educ.,
August 1, 2008;
72(8):
930 - 947.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. J. Ravosa, R. Kunwar, S. R. Stock, and M. S. Stack
Pushing the limit: masticatory stress and adaptive plasticity in mammalian craniomandibular joints
J. Exp. Biol.,
February 15, 2007;
210(4):
628 - 641.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
