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A Histological Evaluation of a Functional Endosseous, Porous-surfaced, Titanium Alloy Dental Implant System in the Dog

Medical Research Council Program in Dental Implantology, Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, Ontario, Canada M5G 1G6

P.A. Watson

Medical Research Council Program in Dental Implantology, Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, Ontario, Canada M5G 1G6

R.M. Pilliar

Medical Research Council Program in Dental Implantology, Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, Ontario, Canada M5G 1G6

T.P. Howley

Medical Research Council Program in Dental Implantology, Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, Ontario, Canada M5G 1G6

J. Winslow

Medical Research Council Program in Dental Implantology, Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, Ontario, Canada M5G 1G6

We have previously reported the clinical and radiographic findings of a trial in dogs of a new dental implant system after a functional period of eight months. The present report consists of the corresponding qualitative and quantitative histological data.

The implant system was fabricated from Ti-6A1-4V and employed a porous-surfaced configuration to achieve implant fixation by bone ingrowth. A similar porous surface was used on the apical 1/3 of the transgingival collar in an attempt to gain ingrowth and attachment of gingival connective tissue. The qualitative histological data confirmed that white such attachment to the collar did occur for some implants, in the majority of implants (22 of 32) the parous region of the collar became contaminated with bacterial plaque, resulting in implant failure (four implants) or suggesting future implant failure (18 implants).

Statistical analyses of the quantitative histological data indicated that there were no significant differences in surface contact of bone with the middle third of the porous implant surface (CLF) when initial healing interval (four or eight weeks), implant location, or aspect of implant (buccal vs. lingual vs. mesial vs. distal) were compared. However, comparison of the current group of functional implants with an earlier group of similarly implanted non-functional implants indicated that function produced a highly significant increase in CLF.

REFERENCES

• Adell, R.; Lekholm, U.; Rockler, B.; and Branemark, P.-I. (1981): A 15-Year Study of Osseointegrated Implants in the Treatment of the Edentulous Jaw, Int J Oral Surg 6:387-416.
• Albrektsson, T.; Brånemark, P.I.; Hansson, H.A.; and Lindstrom, J. (1981): Osseointegrated Titanium Implants. Requirements for Ensuring a Long-Lasting, Direct Bone-to-Implant Anchorage in Man, Acta Orthop Scand 52:155-170.
• Binderman, I.; Shimshoni, Z.; and Somjen, D. (1984): Biochemical Pathways Involved in the Translation of Physical Stimulus into Biological Messages, Calcif Tissue Int 36:582-585.
• Bobyn, J.D.; Cameron, H.U.; Abdulla, D.; Pilliar, R.M.; and Weatherly, G.C. (1982): Biologic Fixation and Bone Modeling with an Unconstrained Canine Total Knee Prosthesis, Clin Orthop 166:301-312.
• Bobyn, J.D.; Pilliar, R.M.; Binnington, A.G.; and Szivek, J.A. (1985): The Effect of Partially and Fully Porous Coated Hip Stem Design on Biological Fixation and Adaptive Bone Remodeling, Trans 31st Orthop Res Soc, Las Vegas, Jan. 21-24, p. 170.
• Carter, D.R. (1984): Mechanical Loading Histories and Cortical Remodeling, Calcif Tissue Int 36:519-524.
• Carter, D.R.; Harris, W.H.; Vasu, R.; and Caler, W.E. (1981a): The Mechanical and Biological Response of Cortical Bone to in vivo Strain Histories. In: Mechanical Properties of Bone, Vol. 45, S.R. Cowin, Ed., New York: American Society of Mechanical Engineering, pp. 81-91.
• Carter, D.R.; Vasu, R.; and Harris, W.H. (1981b): The Plated Canine Femur-Relationships Between the Changes in Bone Stresses and Bone Loss, Acta Orthop Scand 52:241-248.[Medline] [Order article via Infotrieve]
• Chamay, A. and Tschantz, P. (1972): Mechanical Influences in Bone Remodeling. Experimental Research on Wolff's Law, J Biomechan 5:173-180.[CrossRef][Medline] [Order article via Infotrieve]
• Churches, A.E.; Howlett, C.R.; Waldron, K.J.; and Ward, G.W. (1979): The Response of Living Bone to Controlled Time-Varying Loading: Method and Preliminary Results, J Biomechan 12:35-45.[CrossRef][Medline] [Order article via Infotrieve]
• Davidovitch, Z.; Shanfeld, J.L.; Montgomery, P.C.; Lally, E.; Laster, L.; Furst, L.; and Korostoff, E. (1984): Biochemical Mediators of the Effects of Mechanical Forces and Electric Currents on Mineralized Tissues, Calcif Tissue Int 36:586-597.[Medline] [Order article via Infotrieve]
• Deporter, D.A.; Friedland, B.; Watson, P.A.; Pilliar, R.M.; Howley, T.P.; Abdulla, D.; Melcher, A.H.; and Smith, D.C. (1986a): A Clinical and Radiographic Assessment of a Porous-surfaced, Titanium Alloy Dental Implant System in Dogs, J Dent Res 65:1071-1077.[Abstract/Free Full Text]
• Deporter, D.A.; Watson, P.A.; Pilliar, R.M.; Melcher, A.H.; Winslow, J.; Howley, T.P.; Hansel, P.; Maniatopoulos, C.; Rodriguez, A.; Abdulla, D.; Parisien, K.; and Smith, D.C. (1986b): A Histological Assessment of the Initial Healing Response Adjacent to Porous-surfaced Titanium Alloy Dental Implants in Dogs, J Dent Res 65:1064-1070.[Abstract/Free Full Text]
• Deporter, D.A.; Pilliar, R.M.; Watson, P.A.; and Parisien, K. (1988): Radiographic and Morphometric Assessment of a Porous-coated Implant System in Dogs, J Dent Res 67 (Spec Iss):347, Abstr. #1876.
• Engh, C.A. and Bobyn, J.D. (1985): Biological Fixation in Total Hip Arthroplasty. Thorofare, N.J.: Slack, Inc.
• Engh, C.A. and Bobyn, J.D. (1987): A Study of Factors Governing Bone Ingrowth, Stress Shielding and Clinical Results with Porous Coated Hip Replacement, J Bone Joint Surg (accepted for publication).
• Goodship, A.E.; Lanyon, L.E.; and McFie, H. (1979): Functional Adaptation of Bone to Increased Stress, J Bone Joint Surg 61A:539-546.[Abstract/Free Full Text]
• Hassler, C.R.; Rybicki, E.F.; Cummings, K.D.; and Clark, L.C. (1980): Quantification of Bone Stresses During Remodeling, J Biomechan 13:185-190.[CrossRef][Medline] [Order article via Infotrieve]
• Hayes, W.C. and Snyder, B. (1981): Toward a Quantitative Formulation of Wolff's Law in Trabecular Bone. In: Mechanical Properties of Bone, Vol. 45, S.R. Cowin, Ed., New York: American Society of Mechanical Engineering, pp. 43-68.
• James, R.A. and Keln, E.E. (1974): A Histopathological Report on the Nature of the Epithelium and Underlying Connective Tissue Which Surround Oral Implants, J Biomed Mater Res 8:373-383.[Medline] [Order article via Infotrieve]
• Kim, W.C.; Hermens, K.A.; Rechl, H.; Kabo, M.; and Arus-Tutz, H.C. (1986): The Effect of Weight Bearing on Canine Porous Hip Implants, Trans 32nd Orthop Res Soc, New Orleans, Feb. 17-20, p. 490.
• Lanyon, L.E. (1981): The Measurement and Biological Significance of Bone Strain in vivo. In: Mechanical Properties of Bone, Vol. 45, S.R. Cowin, Ed., New York: American Society of Mechanical Engineering, pp. 81-91.
• Lanyon, L.E.; Paul, I.L.; Rubin, C.T.; Thrasher, E.H.; de Laura, R.; Rose, R.M.; and Radin, E.L. (1981): In vivo Measurements from Bone and Prosthesis Following Total Hip Replacement, J Bone Joint Surg 63A:989-1001.[Free Full Text]
• Lanyon, L.E.; Goodship, A.E.; Pye, C.J.; and McFie, J.H. (1982): Mechanically Adaptive Bone Remodeling, J Biomechan 15:141-154.[CrossRef][Medline] [Order article via Infotrieve]
• Lekholm, U.; Adell, R.; Lindhe, J.; Branemark, P.I.; Er-Iksson, B.; Rockler, B.; Lindvall, A.M.; and Yone-Yama, T. (1986): Marginal Tissue Reactions at Osseointegrated Titanium Fixtures. II. A Cross-Sectional Retrospective Study, Int J Oral Maxillofac Surg 15:53-61.[Medline] [Order article via Infotrieve]
• Listgarten, M.A. and Lai, C.H. (1975): Ultrastructure of the Intact Interface Between and Endosseous Epoxy Resin Dental Implant and the Host Tissue, J Biol Buccale 3:13-28.[Medline] [Order article via Infotrieve]
• Maniatopoulos, C.; Rodriguez, A.; Deporter, D.A.; and Melcher, A.H. (1986): An Improved Method for Preparing Histological Sections of Metallic Implants, J Int Oral Maxillofac Implantol 1:31-37.
• Miller, J.; Burke, D.L.; Stachiewicz, J.; and Kelebay, L. (1976): The Fixation of Major Load-Bearing Metal Prostheses to Bone-An Experimental Study Comparing Smooth to Porous Surfaces in a Weight-Bearing Mode, Trans 22nd Orthop Res Soc, New Orleans, Jan. 28-30, p. 52.
• Pilliar, R.M.; Cameron, H.U.; Binnington, A.G.; and Szivek, J. (1979): Bone Ingrowth and Stress Shielding with a Porous Surface Coated Fracture Fixation Plate, J Biomed Mater Res 13:799-810.[CrossRef][Medline] [Order article via Infotrieve]
• Szivek, J.A.; Weatherly, G.C.; Pilliar, R.M.; and Cameron, H.U. (1981): A Study of Bone Remodeling Using Metal-Polymer Laminates, J Biomed Mater Res 15:853-865.[Medline] [Order article via Infotrieve]
• Woo, S.L.-Y.; Kuei, S.C.; Amiel, D.; Gomez, M.A.; Hayes, W.C.; White, F.C.; and Akeson, W.H. (1981): The Effect of Prolonged Physical Training on the Properties of Long Bone: A Study of Wolff's Law, J Bone Joint Surg 63A:780-787.[Abstract/Free Full Text]
• Young, F.A.; Spector, M.; and Kresch, C.H. (1979): Porous Titanium Endosseous Dental Implants in Rhesus Monkeys: Microradiography and Histological Evaluation, J Biomed Mater Res 13:843-856.[Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 67, No. 9, 1190-1195 (1988)
DOI: 10.1177/00220345880670090801


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