|
Sign In to gain access to subscriptions and/or personal tools.
|
Homology of Glucosyltransferase Gene and Protein Sequences from Streptococcus sobrinus and Streptococcus mutans
R.R.B. Russell
Dental Research Unit, Royal College of Surgeons of England, Downe, Kent BR6 7JJ, United Kingdom
T. Shiroza
Department of Microbiology-Immunology, Northwestern University Medical School, Chicago, Illinois 60611, USA
H.K. Kuramitsu
Department of Microbiology-Immunology, Northwestern University Medical School, Chicago, Illinois 60611, USA
J.J. Ferreti
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA
The sequences of glucosyltransferase genes from Streptococcus sobrinus (gtfI) and Streptococcus mutans (gtfB) were compared and show a high degree of homology. There is a 57.7% homology of nucleotides in the genes and a 56. 7% homology of amino acids in the deduced protein sequences. The G + C content for the protein-coding region is 43.6% for S. sobrinus and 41.2% for S. mutans. Internal repeating sequences present in both proteins exhibit some difference in sequence pattern.
REFERENCES
- Birbeck, T.H. and Penn, C.W. (1986): Antigenic Variation in Infectious Diseases. Washington, D.C.: IRL Press.
- Ciardi, J.E. (1983): Purification and Properties of Glucosyltransferases of Streptococcus mutans. In: Glucosyltransferases, Glucans, Sucrose and Dental Caries, R.J. Doyle and J.E. Ciardi, Eds., Special Supplement to Chemical Senses, Washington, D.C.: IRL Press, pp. 51-64.
- Coykendall, A.L. and Gustafson, K.B. (1986): Taxonomy of Streptococcus mutans. In: Molecular Microbiology and Immunobiology of Streptococcus mutans, S. Hamada, S.M. Michalek, H. Kiyono, L. Menaker, and J.R. McGhee, Eds., New York: Elsevier, pp. 21-28.
- Dayhoff, M.O.; Hunt, L.T.; Barker, W.C.; Schwartz, R.M.; and Orcutt, B.C. (1978): Atlas of Protein Sequence and Structure, Vol. 5, Washington, D.C.: National Biomedical Research Foundation.
- Fahnestock, S.R.; Alexander, P.; Nagle, J.; and Filpula, D. (1986): Gene for an Immunoglobulin-binding Protein from a Group G Streptococcus, J Bacteriol 167:870-880.[Abstract/Free Full Text]
- Ferretti, J.J.; Gilpin, M.L.; and Russell, R.R.B. (1987): Nucleotide Sequence of the Glucosyltransferase Gene From Streptococcus sobrinus MFe28, J Bacteriol 169:4271-4278.[Abstract/Free Full Text]
- Fischetti, V.A.; Jones, K.F.; and Scott, J.R. (1985): Size Variation of the M Protein in Group A Streptococci, J Exp Med 161:1384-1401.[Abstract/Free Full Text]
- Fukumori, F.; Sashihara, N.; Kudo, T.; and Horikoshi, K. (1986): Nucleotide Sequences of Two Cellulase Genes from Alkalophilic Bacillus sp. Strain N-4 and Their Strong Homology, J Bactetiol 168:479-485.
- Grahame, D.A. and Mayer, R.M. (1985): Purification and Comparison of Two Forms of Dextransucrase from Streptococcus sanguis, Carbohyd Res 147:19-133.
- Guss, B.; Eliasson, M.; Olsson, 0.; Uhlen, M.; Frej, A.-K.; Jornvall, H.; Flock, J.-I.; and Lindberg, M. (1986): Structure of the IgG-binding Regions of Streptococcal Protein G, EMBO Journal 5:1567-1575.[Medline]
[Order article via Infotrieve]
- Hamada, S. and Slade, H.D. (1980): Biology, Immunology, and Cariogenicity of Streptococcus mutans, Microbiol Rev 44:331-384.[Free Full Text]
- Hanada, N.; Takehara, T.; and Saeki, E. (1987): Purification and Characterization of a Third Glucosyltransferase from Streptococcus mutans Serotype g. J Gen Microbiol 133:1351-1358.[Abstract/Free Full Text]
- Hollingshead, S.K.; Fischetti, V.F.; and Scott J.R. ( 1986): Complete Nucleotide Sequence of Type 6M Protein of the Group A Streptococcus, Repetitive Structure and Membrane Anchor, J Biol Chem 261:1677-1686.[Abstract/Free Full Text]
- Ikemura, T. (1981): Correlation Between the Abundance of Escherichia coli Transfer RNAs and the Occurrence of the Respective Codons in its Protein Genes, J Molec Biol 146:1-21.[CrossRef][Medline]
[Order article via Infotrieve]
- Ikemura, T. (1985): Codon Usage, tRNA Content, and Rate of Synonymous Substitution. In: Population Genetics and Molecular Evolution, J. Ohta and K. Aoki, Eds., Berlin: Springer Verlag, pp. 385-406.
- Kimura, M. (1980): A Simple Method for Estimating Evolutionary Rates of Base Substitutions Through Comparative Studies of Nucleotide Sequences, J Molec Evol 16:111-120.
- Loesche, W.J. (1986): Role of Streptococcus mutans in Human Dental Decay, Microbiol Rev 50:353-380.[Free Full Text]
- Miller, A.W.; Eklund, S.H.; and Robyt, J.R. (1986): Milligram to Gram Scale Purification and Characterization of Dextransucrase from Leuconostoc mesenteroides NRRL B-512F, Carbohyd Res 147:119-133.[CrossRef][Medline]
[Order article via Infotrieve]
- Mukasa, H. (1986): Properties of Streptococcus mutans Glucosyltransferases. In: Molecular Microbiology and Immunobiology of Streptococcus mutans, S. Hamada, S. Michalek, H. Kiyono, L. Menaker, and J.R. McGhee, Eds., New York: Elsevier, pp. 121-132.
- Muto, A. and Osawa, S. (1987): The Guanine and Cytosine Content of Genomic DNA and Bacterial Evolution, Proc Natl Acad Sci USA 84:166-169.[Abstract/Free Full Text]
- Pugsley, A.P. and Schwartz, M. (1985): Export and Secretion of Proteins by Bacteria, FEMS Microbiol Rev 32:3-38.[CrossRef]
- Pustell, J. and Kafatos, F.C. (1986): A Convenient and Adaptable Microcomputer Environment for DNA and Protein Sequence Manipulation and Analysis, Nucl Acids Res 14:479-488.[Abstract/Free Full Text]
- Russell, R.R.B.; Gilpin, M.L.; Mukasa, H.; and Dougan, G. (1987): Characterization of Glucosyltransferase from a Streptococcus sobrinus Gene Cloned in Escherichia coli, J Gen Microbiol 133:935-944.[Abstract/Free Full Text]
- Shiroza, T.; Ueda, S.; and Kuramitsu, H.K. (1987): Sequence Analysis of the gtfB Gene from Streptococcus mutans, J Bacteriol 169:4263-4270.[Abstract/Free Full Text]
- Uhlen, M.; Guss, B.; Nilsson, B.; Gatenbeck, S.; Philipson, L.; and Lindberg, M. (1984): Complete Sequence of the Staphylococcal Gene Encoding Protein A. A Gene Evolved Through Multiple Duplications, J Biol Chem 259:1695-1702.[Abstract/Free Full Text]
- Warren, G.; Coretto, L.; and Wobler, P. (1986): Conserved Repeats in Diverged Ice Nucleation Structural Genes from Two Species of Pseudomonas, Nucl Acids Res 14:8047-8059.[Abstract/Free Full Text]
- Wilbur, W.J. and Lipman, D.J. (1983): Rapid Similarity Searches of Nucleic Acid and Protein Data Banks, Proc Natl Acad Sci USA 80:726-730.[Abstract/Free Full Text]
Journal of Dental Research, Vol. 67, No. 3,
543-547 (1988)
DOI: 10.1177/00220345880670030401
 CiteULike  Complore  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter What's this?
This article has been cited by other articles:
|
|
|
|
 
Y. Niu, J. Sun, M. Fan, Q.-A. Xu, J. Guo, R. Jia, and Y. Li
Construction of a New Fusion Anti-caries DNA Vaccine
Journal of Dental Research,
May 1, 2009;
88(5):
455 - 460.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. J. Smith, W. F. King, L. A. Barnes, D. Trantolo, D. L. Wise, and M. A. Taubman
Facilitated Intranasal Induction of Mucosal and Systemic Immunity to Mutans Streptococcal Glucosyltransferase Peptide Vaccines
Infect. Immun.,
August 1, 2001;
69(8):
4767 - 4773.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. J. Smith, W. F. King, and R. Godiska
Passive Transfer of Immunoglobulin Y Antibody to Streptococcus mutans Glucan Binding Protein B Can Confer Protection against Experimental Dental Caries
Infect. Immun.,
May 1, 2001;
69(5):
3135 - 3142.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. A. Taubman, D. J. Smith, C. J. Holmberg, and J. W. Eastcott
Coimmunization with Complementary Glucosyltransferase Peptides Results in Enhanced Immunogenicity and Protection against Dental Caries
Infect. Immun.,
May 1, 2000;
68(5):
2698 - 2703.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Jespersgaard, G. Hajishengallis, T. E. Greenway, D. J. Smith, M. W. Russell, and S. M. Michalek
Functional and Immunogenic Characterization of Two Cloned Regions of Streptococcus mutans Glucosyltransferase I
Infect. Immun.,
February 1, 1999;
67(2):
810 - 816.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. J. Smith, W. F. King, C. D. Wu, B. I Shen, and M. A. Taubman
Structural and Antigenic Characteristics of Streptococcus sobrinus Glucan Binding Proteins
Infect. Immun.,
November 1, 1998;
66(11):
5565 - 5569.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
