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Journal of Dental Research
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Changes of Secretory Ameloblasts in Mini-pig Fetuses Exposed to Ethanol in vivo

M.E. Matthiessen

Anatomy Department A, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark

P. Rømert

Anatomy Department C, The Panum Institute, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark

After addition of ethanol to the ordinary fodder of pregnant mini-pigs, ultrastructural changes were found in secretory ameloblasts from tooth germs of their mid-term fetuses. Compared with controls, many mitochondria showed abnormal shape and size, and some exhibited deposition of paracrystalline material in the matrix. An abnormal deposition of stippled material intercellularly was also observed. These changes were interpreted as signs of an abnormal secretory function.

REFERENCES

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  • Ghadially, F.N. (1982): Mitochondria. In: Ultrastructural Pathology of the Cell, 2nd ed., London: Butterworths, pp. 149-263.
  • Kallenbach, E. (1979): Microscopy of Tetracycline-induced Lesions in the Rat Incisor Enamel Organ, Arch Oral Biol 24:869-876.[Medline] [Order article via Infotrieve]
  • Matthiessen, M.E. and Rømert, P. (1976): The Secretory Ameloblast of the Mini-Pig Foetus, Cell Tissue Res 169:179-192.[Medline] [Order article via Infotrieve]
  • Matthiessen, M.E. and Rømert, P. (1980): Ultrastructure of the Human Enamel Organ, Cell Tissue Res 205:371-382.[Medline] [Order article via Infotrieve]
  • Moe, H. and Mikkelsen, H. (1977): Light Microscopical and Ultrastructural Observations on the Effect of Vinblastine on Ameloblasts of Rat Incisors in vivo, Acta Pathol Microbiol Scand Sect A 85:73-88.
  • Petersen, P. (1977): Abnormal Mitochondria in Hepatocytes in Human Fatty Liver, Acta Pathol Microbiol Scand Sect A 85:413-420.
  • Rømert, P. and Matthiessen, M.E. (1983a): Alcohol-induced Injury of Mitochondria in Hepatocytes of Mini-Pig Fetuses, Virchows Arch (Pathol Anat) 399:299-305.
  • Rømert, P. and Matthiessen, M.E. (1983b): Ethanol-induced Changes of Granular Endoplasmic Reticulum in Hepatocytes of Mini-Pig Foetuses, Acta Pathol Microbiol Immunol Scand Sect A 91:413-417.[Medline] [Order article via Infotrieve]
  • Westergaard, J. (1980): Structural Changes Induced by Tetracycline in Secretory Ameloblasts in Young Rats, Scand J Dent Res 88:481-495.[Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 67, No. 11, 1402-1404 (1988)
DOI: 10.1177/00220345880670110801


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This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Matthiessen, M.E.
Right arrow Articles by Rømert, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Matthiessen, M.E.
Right arrow Articles by Rømert, P.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH
Hazardous Substances DB
*ETHANOL
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?