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Improvement of the Caries Resistance of Human Dental Roots by a Two-step Conversion of the Root Mineral into Fluoridated HydroxylapatiteDental School, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
Dental School, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
Dental School, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
Dental School, University of Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands Roots of extracted human molars were treated for both 10 and 30 min with a saturated solution of dicalcium phosphate dihydrate (DCPD) of pH 2.4 and subsequently with a 5.3 mmol.L -1 solution of sodium fluoride of pH 7.0. The objective of these combined treatments was to convert the highly-soluble root mineral into the less-soluble fluoridated hydroxylapatite, with DCPD as an intermediate, to improve caries resistance. The mineral content of the surface layer was not affected in a significant way. Roots treated in this way were subjected to 50 mmol.L-1 acetate buffer solutions of pH 5.5 and with pIOHA-values of 112, 116, and 122. The proportional reduction of the rate of demineralization (Vdem) of similarly treated roots subjected to buffer solutions of pIOHA 112 and 116 appeared to be equal initially. Since fluoridated hydroxylapatite is insoluble under these conditions, these findings are in agreement with expectations. The reduction of Vdem amounted to about 45 and 70% for roots treated for 10 and 30 min, respectively. When roots were treated for 10 and 30 min and then exposed to buffer solutions with a pIOHA 122, reductions of Vdem of about 30 and 55%, respectively, were found. Conversion of the root mineral into fluoridated hydroxylapatite can eliminate, in principle, the existing difference in caries susceptibility of the root and of the dental enamel. REFERENCES
Journal of Dental Research, Vol. 67, No. 10,
1254-1256 (1988) This article has been cited by other articles:
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