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The Influence of Aging on Lysosomal Acid DNase of the Rat Submandibular Gland

Department of Oral Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830, Japan

R. Ogura

Department of Medical Biochemistry, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830, Japan

T. Kameyama

Department of Oral Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830, Japan

C. Sujaku

Department of Oral Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830, Japan

J. Tonzetich

Department of Oral Biology, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z7

Lysosomal and cytoplasmic fractions were prepared from rat submandibular glands for investigation of the release of lysosomal acid DNase in relation to aging. It was found that the acid DNase activity ratio for cytoplasmic/lysosomal fractions in rats aged 27 months was higher than that in three-month-old rats. The release of acid DNase from the lysosomal fraction by shaking was markedly increased in the fraction from the older animals.

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Journal of Dental Research, Vol. 67, No. 1, 82-84 (1988)
DOI: 10.1177/00220345880670011601


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Yaegak, K. Articles by Tonzetich, J. Search for Related Content PubMed PubMed Citation Articles by Yaegak, K. Articles by Tonzetich, J. Social Bookmarking                         What's this?