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Development of an Intra-oral Single-section Remineralization Model
J.S. Wefel
Dows lnstitute for Dental Research, College of Dentistry, University of Iowa, Iowa City, Iowa 52242
G.J. Maharry
Dows lnstitute for Dental Research, College of Dentistry, University of Iowa, Iowa City, Iowa 52242
M.E. Jensen
Dows lnstitute for Dental Research, College of Dentistry, University of Iowa, Iowa City, Iowa 52242
J.D. Harless
Dows lnstitute for Dental Research, College of Dentistry, University of Iowa, Iowa City, Iowa 52242
An intra-oral model system has been developed which uses a single-section technique for before-and-after measurements on the same tissue. This model allows for placement of sections of enamel at both buccal and approximal sites. These sections may be sound or possess white-spot lesions. This allows for the evaluation of lesion initiation, lesion progression, and/or lesion remineralization. The sections are appropriate for measurement by polarized light microscopy, and, although not included in this study, they are also suitable for microradiographic evalution.
With ten human volunteers, the model system was evaluated by means of three rinse regimens in a cross-over design. The distilled water rinse showed the whole range of possible changes (e.g., demineralization, no change, and remineralization). More consistent remineralization was observed when a fluoride rinse or a remineralizing fluid was used. This model system should prove to be quite useful in evaluation of demineralization and remineralization phenomena in the oral environment.
REFERENCES
- Backer-Dirks, O. (1966): Post-eruptive Changes in Dental Enamel, J Dent Res 45:443-452.
- Brudevold, F.; Attarzadeh, F.; Tehrani, A.; Van Houte, J.; and Russo, J. (1984): Development of New Intraoral Demineralization Test, Caries Res 18:421-429.[Medline]
[Order article via Infotrieve]
- Dijkman A.G.; Schuthof, J.; and Arends, J. (1986): In vivo Remineralization of Plaque-induced Initial Enamel Lesions-A Microradiographic Investigation, Caries Res 20:202-208.[Medline]
[Order article via Infotrieve]
- Feagin, F. (1971): Calcium, Phosphate and Fluoride Deposition on Enamel Surfaces, Calcif Tissue Res 8:154-164.[Medline]
[Order article via Infotrieve]
- Feagin, F.F.; Gonzalez, M.; and Jeansonne, B.G. (1972): Kinetic Reactions of Calcium, Phosphate and Fluoride Ions at the Enamel Surface-Solution Interface, Calcif Tissue Res 10:113-127.[Medline]
[Order article via Infotrieve]
- Featherstone, J.D.B.; Cutress, T.W.; Rodgers, B.E.; and Dennison, P.J. (1982): Remineralization of Early Carious Lesions in vivo by a Self-administered Mouthrinse or Paste, Caries Res 16:235-242.[Medline]
[Order article via Infotrieve]
- Gelhard, T.B.F.M. and Arends, J. (1984a): In vivo Remineralization of Artificial Subsurface Lesions in Human Enamel I, J Biol Buccale 12:49-52.[Medline]
[Order article via Infotrieve]
- Gelhard, T.B.F.M. and Arends, J. (1984b): Microradiography of in vivo Remineralized Lesions in Human Enamel II, J Biol Buccale 12:59-65.[Medline]
[Order article via Infotrieve]
- Head, J.A. (1912): A Study of Saliva and Its Action on Tooth Enamel in Reference to its Hardening and Softening, J Am Med Assoc 59:2118-2122.
- Klinger, H.G. and Wiedemann, W. (1986): Enhancement of in vivo Remineralization of Approximal Initial Caries in Man by an Organic and Inorganic Remineralization Agent, Arch Oral Biol 31:269-272.[Medline]
[Order article via Infotrieve]
- Koulourides, T. (1966): Dynamics of the Tooth Surface Oral Fluid Equilibrium, Adv Oral Biol 2:149-171.[Medline]
[Order article via Infotrieve]
- Koulourides, T.; Phantumvanit, P.; Munksgaard, E.C.; and Housch, T. (1974): An Intraoral Model used for Studies of Fluoride Incorporation in Enamel, J Oral Pathol 3:185-196.[Medline]
[Order article via Infotrieve]
- Silverstone, L.M. (1977): Remineralization Phenomena, Caries Res (Suppl 1) 11:59-84.[Medline]
[Order article via Infotrieve]
- Silverstone, L.M. (1968): The Surface Zone in Caries and in Caries-like Lesions Produced in vitro, Br Dent J 125:145-157.[Medline]
[Order article via Infotrieve]
- ten Cate, J.M. and Arends, J. (1977): Remineralization of Artificial Enamel Lesions in vitro, Caries Res 11:277-286.[Medline]
[Order article via Infotrieve]
- Von Der Fehr, F.R.; Loe, H.; and Theilade, E. (1970): Experimental Caries in Man, Caries Res 4:131-148.[Medline]
[Order article via Infotrieve]
Journal of Dental Research, Vol. 66, No. 9,
1485-1489 (1987)
DOI: 10.1177/00220345870660091401
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