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Journal of Dental Research
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Oxygen Consumption Mediated by M2 Muscarinic Receptors in Rat Salivary Glands

D. Stojic

Department of Pharmacology, Faculty of Stomatology, University of Belgrade, 11000 Belgrade, Yugoslavia

M. Terzic

Department of Pharmacology, Faculty of Stomatology, University of Belgrade, 11000 Belgrade, Yugoslavia

Carbachol and oxotremorine stimulated the consumption of oxygen in rat parotid, submandibular, and sublingual gland slices in a dose-dependent manner. Their actions were abolished by atropine and nifedipine but not by trihexyphenidyl. The findings suggest that carbachol and oxotremorine enhanced oxygen consumption in the major salivary gland slices by the activation of the calcium-dependent muscarinic M2 receptors.

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Journal of Dental Research, Vol. 66, No. 9, 1435-1437 (1987)
DOI: 10.1177/00220345870660090501
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D. Stojic
Carbachol-induced Oxygen Consumption in Slices from Developing Rat Submandibular and Parotid Glands
Journal of Dental Research, August 1, 1998; 77(8): 1647 - 1653.
[Abstract] [PDF]

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