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Micro-electrode Techniques for the Analysis of Oral Fluids
G.L. Vogel
Paffenbarger Research Center, American Dental Association Health Foundation, National Bureau of Standards, Gaithersburg, Maryland 20899
C.M. Carey
Paffenbarger Research Center, American Dental Association Health Foundation, National Bureau of Standards, Gaithersburg, Maryland 20899
L.C. Chow
Paffenbarger Research Center, American Dental Association Health Foundation, National Bureau of Standards, Gaithersburg, Maryland 20899
W.E. Brown
Paffenbarger Research Center, American Dental Association Health Foundation, National Bureau of Standards, Gaithersburg, Maryland 20899
This paper describes the use of micro-electrodes for the analysis of small fluid volumes recovered from the oral environment. The analysis has several advantages: (1) It directly measures the activity of ions, a quantity more relevant to mineral saturation than the conventionally measured concentration, (2) minimum fluid volume for analysis is usually less than 0.005 µL, small enough to avoid sample pooling in most analyses, (3) numerous ions can be measured simultaneously, (4) the analysis time is very short, and (5) the use of mineral oil to isolate specimens provides a simple method for controlling the CO2 tension and humidity over the specimens.
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Journal of Dental Research, Vol. 66, No. 11,
1691-1697 (1987)
DOI: 10.1177/00220345870660111801
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