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Journal of Dental Research
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Effect of X-ray Irradiation on Lipid Peroxide Levels in the Rat Submandibular Gland

M. Nishi

Second Department of Oral and Maxillofacial Surgery, Dental School, Kagoshima University, 1208-1 Usuki-cho, Kagoshima-shi 890, Japan

H. Takashima

Second Department of Oral and Maxillofacial Surgery, Dental School, Kagoshima University, 1208-1 Usuki-cho, Kagoshima-shi 890, Japan

T. Oka

Department of Oral Surgery, Medical School, Fujita Gakuen University, 1-98 Mizukake-cho, Toyoake-shi, Aichi 470-11

N. Ohishi

Institute of Applied Biochemistry, Yagi Memorial Park, Mitake, Gifu 505-01, Japan

K. Yagi

Institute of Applied Biochemistry, Yagi Memorial Park, Mitake, Gifu 505-01, Japan

We examined the effect of local x-ray irradiation on the changes in the lipid peroxide level in submandibular gland, liver, and blood plasma. Rats five weeks of age received a single low dose of 3 Gy x-ray irradiation to their neck regions. The lipid peroxide level in the submandibular gland was significantly enhanced at seven days after irradiation, as was the level in the blood plasma at two hours, seven and 14 days after irradiation. The lipid peroxide level in the liver decreased, as compared with levels in the controls. There was a slight tendency for acinar cells of the submandibular gland to show pyknosis and anomalous nuclei within three days after irradiation. These results suggest that radiation injury results in an elevation of the lipid peroxides in the submandibular gland, and an increased level in the blood.

REFERENCES

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Journal of Dental Research, Vol. 65, No. 7, 1028-1029 (1986)
DOI: 10.1177/00220345860650070701
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This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
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Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Nishi, M.
Right arrow Articles by Yagi, K.
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PubMed
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Right arrow Articles by Nishi, M.
Right arrow Articles by Yagi, K.
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