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Journal of Dental Research
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The Kinetics of Dissolution of Tooth Enamel — A Constant Composition Study

W.C. Chen

Chemistry Department, State University of New York at Buffalo, Buffalo, New York 14214

G.H. Nancollas

Chemistry Department, State University of New York at Buffalo, Buffalo, New York 14214

The kinetics of dissolution of powdered bovine enamel and of human enamel, both untreated and extracted with either hypochlorite or chloroform, has been studied using a constant solution composition technique in undersaturated solutions of calcium phosphate (total molar calcium concentration, TCa = 0.3 to 13.1 x 10-3 mol L-1, total molar phosphate, Tp = 0.18 to 7.9 x 10-3 mol L-1) at an ionic strength of 0.15 mol L-1, and pH = 4.5. The kinetic equations describing the dissolution reactions suggest a surface dislocation mechanism, and the presence of fluoride ion markedly retarded the reaction. For human enamel, a fluoride level of only 0.5 ppm reduced the rate of dissolution ten-fold. In contrast, the dissolution of hydroxyapatite, HAP, is best interpreted in terms of a polynucleation process.

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Journal of Dental Research, Vol. 65, No. 5, 663-668 (1986)
DOI: 10.1177/00220345860650050601
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This Article
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What's this?