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Influence of Soluble Pyrophosphate on Calculus Formation in Adults

Oral Health Research Institute

B.B. Beiswanger

Oral Health Research Institute

G.K. Stookey

Oral Health Research Institute

J.R. Swancar

University of Maryland Dental School, 666 West Baltimore Street, Baltimore, Maryland 21201

D.K. Hennon

Department of Pedodontics, Indiana University School of Dentistry, 415 North Lansing Street, Indianapolis, Indiana 46202

The purpose of this double-blind, longitudinal clinical study was to assess the efficacy of a dentifrice containing 3.3% soluble pyrophosphate in inhibiting calculus formation and its effect upon the oral soft tissues. A total of 265 adult volunteers was given a dental prophylaxis. Each was examined for dental calculus and oral soft tissue pathology. The volunteers were then randomly assigned to use either a dentifrice containing soluble pyrophosphate and sodium fluoride or a placebo sodium fluoride formulation for ad libitum home usage. At the two-month completion of the study, 217 subjects were available for examination. The results showed that the group using the dentifrice containing soluble pyrophosphate experienced a significant 26% decrease in calculus formation as compared with the placebo group, with both dentifrices being equally well-tolerated by the oral soft tissues.

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Journal of Dental Research, Vol. 64, No. 9, 1159-1162 (1985)
DOI: 10.1177/00220345850640091401


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Mallatt, M.E. Articles by Hennon, D.K. Search for Related Content PubMed Articles by Mallatt, M.E. Articles by Hennon, D.K. Social Bookmarking                         What's this?