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Age-related Salivary Flow Rate Changes in Controls and Patients with Oral Lichen Planus
B.K. Gandara
Department of Oral Medicine, SC-63
K.T. Izutsu
Department of Oral Medicine, SC-63, Department of Oral Biology, SB-22, School of Dentistry, University of Washington, Seattle, Washington 98195
E.L. Truelove
Department of Oral Medicine, SC-63
W.Y. Ensign
Department of Oral Biology, SB-22, School of Dentistry, University of Washington, Seattle, Washington 98195
E.E. Sommers
Department of Oral Medicine, SC-63
Unstimulated whole saliva and stimulated whole, parotid, and labial minor gland saliva samples were collected from 25 patients with oral lichen planus and from 25 age- and sex-matched controls between the ages of 25 and 87 years. All subjects did not smoke or chew tobacco, had no serious illnesses, and were unmedicated. There were no significant differences in flow rates between the two groups. However, a significant age-related decrease in labial minor gland saliva flow rate was found in both the lichen planus group and the controls. Flow rates of unstimulated and stimulated whole saliva and stimulated parotid saliva were not related to age in either group.
REFERENCES
- Baum, B.J. (1981): Evaluation of Stimulated Parotid Saliva Flow Rate in Different Age Groups, J Dent Res 60:1292-1296.[Abstract/Free Full Text]
- Ben-Aryeh, H.; Miron, D.; Szargel, R.; and Gutman, D. (1984): Whole Saliva Secretion Rates in Old and Young Healthy Subjects, J Dent Res 63:1147-1148.[Abstract/Free Full Text]
- Bertram, U. (1967): Studies on Salivary Secretion, Acta Odontol Scand (Suppl) 49:13-124.
- Carlson, A.J. and Crittenden, A.L. (1910): The Relation of Ptyalin Concentration to the Diet and to the Rate of Secretion of the Saliva, Am J Physiol 22:169-177.
- Chauncey, H.H.; Borkan, G.A.; Wayler, A.H.; Feller, R.P.; and Kapur, K.K. (1981): Parotid Fluid Composition in Healthy Aging Males, Adv Physiol Sci 28:323-328.
- Crawford, J.M.; Taubman, M.A.; and Smith, D.J. (1975): Minor Salivary Glands as a Major Source of Secretory Immunoglobulin A in the Human Oral Cavity, Science 190:1206-1209.[Abstract/Free Full Text]
- Dawes, C. and Wood, C.M. (1973): The Contribution of Oral Minor Mucous Gland Secretions to the Volume of Whole Saliva in Man, Arch Oral Biol 18:337-342.[CrossRef][Medline]
[Order article via Infotrieve]
- Drummond, J.R. and Chisholm, D.M. (1984): A Qualitative and Quantitative Study of the Aging Human Labial Salivary Glands, Arch Oral Biol 29:151-155.[CrossRef][Medline]
[Order article via Infotrieve]
- Eversole, L.R. (1972): The Histochemistry of Mucosubstances in Human Minor Salivary Glands, Arch Oral Biol 17:1225-1239.[CrossRef][Medline]
[Order article via Infotrieve]
- Gutman, D. and Ben-Aryeh, H. (1974): The Influence of Age on Salivary Contents and Rate of Flow, Int J Oral Surg 3:314-317.[Medline]
[Order article via Infotrieve]
- Heft, M.W. and Baum, B.J. (1984): Unstimulated and Stimulated Parotid Salivary Flow Rate in Individuals of Different Ages, J Dent Res 63:1182-1185.[Abstract/Free Full Text]
- Izutsu, K.T.; Menard, T.W.; Schubert, M.M.; Ensign, W.Y.; Sullivan, K.; Truelove, E.L.; and Thomas, E.D. (1985): Graft Versus Host Disease Related Secretory IgA Deficiency in Bone Marrow Transplant Recipients: Findings in Labial Saliva, Lab Invest 52:292-297.[Medline]
[Order article via Infotrieve]
- Kim, J. and Kohout, F.J. (1975): Analysis of Variance and Co-variance: Subprograms ANOVA and Oneway. In: SPSS Statistical Package for the Social Sciences, 2nd ed., Nie, N.H.; Hull, C.H.; Jenkins, J.G.; Steinbrenner, K.; and Bent, D.H.: Eds., New York: McGraw-Hill, pp. 398-421.
- Lundstrom, I.M.C.; Anneroth, G.B.; and Bergstedt, H.F. (1982): Salivary Gland Function and Changes in Patients with Oral Lichen Planus, Scand J Dent Res 90:443-458.[Medline]
[Order article via Infotrieve]
- Milne, R.W. and Dawes, C. (1973): The Relative Contributions of Different Salivary Glands to the Blood Group Activity of Whole Saliva in Humans, Vox Sang 25:298-307.[Medline]
[Order article via Infotrieve]
- Parvinen, T. and Larmas, M. (1982): Age Dependency of Stimulated Salivary Flow Rate, pH, and Lactobacillus and Yeast Concentrations, J Dent Res 61:1052-1055.[Abstract/Free Full Text]
- Scott, J. (1980): Qualitative and Quantitative Observations on the Histology of Human Labial Salivary Glands Obtained Post Mortem, J Biol Buccale 8:187-200.[Medline]
[Order article via Infotrieve]
- Syrjanen, S. (1984): Age-related Changes in Structure of Labial Minor Salivary Glands, Age Aging 13:159-165.[Abstract/Free Full Text]
- Tandler, B.; Denning, C.R.; Mandel, I.D.; and Kutscher, A.H. (1969): Ultrastructure of Human Labial Salivary Glands. I. Acinar Secretory Cells, J Morphol 127:383-408.
- Tabak, L.A.; Levine, M.J.; Mandel, I.D.; and Ellison, S.A. (1982): Role of Salivary Mucins in the Protection of the Oral Cavity, J Oral Pathol 11:1-17.[Medline]
[Order article via Infotrieve]
Journal of Dental Research, Vol. 64, No. 9,
1149-1151 (1985)
DOI: 10.1177/00220345850640091101

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