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Journal of Dental Research
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Erythema Multiforme and Herpes Simplex Virus

F. Lozada-Nur

Department of Stomatology, S-647, School of Dentistry, 515 Parnassus Ave., University of California, San Francisco, California 94143

E.J. Shillitoe

Department of Microbiology, The University of Texas Health Science Center at Houston, P.O. Box 20068, Houston, Texas 77225

It has been suggested that herpes simplex virus (HSV) can trigger erythema multiforme (EM) at different times. One recent study showed HSV antigen in immune complexes of patients with EM. The purpose of our study was to assess a possible association between EM and HSV. Sixteen patients and 16 matched controls were studied using an enzyme-linked immunosorbent assay (ELISA) to measure antibody of the IgG, IgA, and IgM classes against HSV-1. From our study on patients with oral erythema multiforme, we found no evidence to correlate the occurrence and/or severity of EM and the HSV-1.

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Journal of Dental Research, Vol. 64, No. 6, 930-931 (1985)
DOI: 10.1177/00220345850640061501
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This Article
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Right arrow Articles by Shillitoe, E.J.
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What's this?