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Journal of Dental Research
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Analysis of Covariance in Caries Clinical Trials using Groupings of Teeth

H.V. Worthington

Dental Health Unit, Turner Dental School, University of Manchester, Bridgeford Street, Manchester, England M15 6FH

B.L. Adkins

Social Science, University of Queensland, St. Lucia, Australia

An empirical investigation was carried out on data from four caries clinical trials of subjects who were initially 11 to 12 years old. The three baseline variables suggested by Adkins (1977), as possibly being related to caries increment, were each calculated on specific groupings of teeth, and these were then considered as predictor variables for the dependent variable, caries increment.

A gain in efficiency of approximately 20% was obtained when an analysis of covariance was used with these predictor variables, over a straightforward analysis of variance. However, this was only slightly more efficient than using baseline DMFS as a covariable. This investigation did not support the results of initial work done by Adkins (1977).

REFERENCES

  • Adkins, B.L. (1977): Methodological Developments for Clinical Trials, J Dent Res 50(C):130-135.
  • Grainger, R.M.; Lehnhoff, R.W.; Bollmer, B.W.; and Zacherl, W.A. (1984): Analysis of Covariance in Dental Caries Clinical Trials, J Dent Res 63(Spec Iss):766-771.[Medline] [Order article via Infotrieve]
  • Howat, A.P.; Holloway, P.J.; and Davies, T.G.H. (1978): Caries Prevention by Daily Supervised Use of a MFP Gel Dentifrice, Br Dent J 145:233-235.[CrossRef][Medline] [Order article via Infotrieve]
  • Lu, K.H. (1966): An Experimentally Supported "Law of Tooth Decay" and its Application, Arch Oral Biol 11:757-768.[CrossRef][Medline] [Order article via Infotrieve]
  • Mitropoulos, C.M.; Davies, T.G.H.; and Worthington, H.V. (1984): Relative Efficacy of Dentifrices Containing 250 or 1000 ppm F in Preventing Dental Caries - Report of 32 month Clinical Trial, Community Dent Health 1:193-200.[Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 64, No. 2, 102-105 (1985)
DOI: 10.1177/00220345850640020101


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This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Worthington, H.V.
Right arrow Articles by Adkins, B.L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Worthington, H.V.
Right arrow Articles by Adkins, B.L.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?