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Effect of Some Salts of Calcium, Sodium, Potassium, and Strontium on Intra-oral Enamel Demineralization
F. Brudevold
Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
A. Tehrani
Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
F. Attarzadeh
Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
D. Goulet
Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
J. Van Houte
Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
A newly-developed intra-oral enamel demineralization test was used to evaluate the effect of supplementation of a 10% sucrose solution with various components on enamel demineralization induced by the sucrose. Five human subjects wore a palatal prosthesis holding eight blocks of subsurface bovine enamel covered with a layer of S. mutans cells. The test involved rinsing with sucrose solution or with sucrose solution supplemented with 0.162 mol/l of different calcium salts or equivalent concentrations of Na-, K-, and Sr salts; rinsing was for one min at times zero and 45 min of the 90-minute test period. Ca-propionate, Ca-acetate, and Ca-levulinate completely inhibited sucrose-induced enamel demineralization; Ca-chloride, Ca-lactate, and Ca-ascorbate gave from 65-75%, and K-acetate, Nalactate, and Sr-lactate 39, 25, and 18% inhibition, respectively. Consideration of the anion dissociation constants and the Ca-anion association constants of the salts suggests that the observed inhibition is caused mainly by common ion effects and, to a lesser extent, by buffer effects.
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Journal of Dental Research, Vol. 64, No. 1,
24-27 (1985)
DOI: 10.1177/00220345850640010401
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