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Neuraminidase Activity: A Biochemical Marker to Distinguish Streptococcus mitis from Streptococcus sanguis
P.A. Murray
Department of Oral Biology
M.J. Levine
Department of Oral Biology
L.A. Tabak
Department of Endodontics, School of Dentistry, State University of New York at Buffalo, 312 Cary Hall, Buffalo, New York 14214
M.S. Reddy
Department of Oral Biology
Selected reference and freshly isolated strains of Streptococcus mitis (mitior) and Streptococcus sanguis were assayed for cell-associated neuraminidase activity by their ability to hydrolyze [3H-] sialyllactitol. A cell-associated neuraminidase was detected with S. mitis and S. sanguis serotype II (reclassified as S. mitis) but not with S. sanguis serotypes I and III. Neuraminidase activity of S. mitis correlated with this organism's inability to hydrolyze arginine, aesculin, and few, if any, sugars. The findings indicate that the presence of cell-associated neuraminidase activity is useful for the taxonomic classification of S. mitis.
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Journal of Dental Research, Vol. 63, No. 2,
111-113 (1984)
DOI: 10.1177/00220345840630020201

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