This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Winters, W.D. Articles by McAnear, J.T. Search for Related Content PubMed PubMed Citation Articles by Winters, W.D. Articles by McAnear, J.T. Social Bookmarking                         What's this?

Clinical Science Humoral Immune Responses to Adenoviruses, Herpes Virus Type 1, and Candida albicans in Sera of Dental Patients with Oral Neoplastic and Periodontal Diseases

Departments of Microbiology and Diagnostic Dental Sciences, University of Texas Health Science Center at San Antonio

G.F. Guest

Departments of Microbiology and Diagnostic Dental Sciences, University of Texas Health Science Center at San Antonio

J.T. McAnear

Dental Service, Audie Murphy Memorial VA Hospital, San Antonio, Texas 78284

Levels of immunoglobulin class-specific antibodies as determined by solid phase radioimmunoassays to herpes simplex virus type 1 (HSV-1), human adenovirus types 5, 21, and 31 and to Candida albicans in sera from untreated healthy dental patients were not significantly different from levels of these antibodies in sera from untreated dental patients with benign oral tumors, oral carcinoma, or periodontal disease. These results show that higher levels of immunoglobulin class-specific antibodies to HSV-1, the three adenoviruses, or Candida albicans are not a consistent finding in sera from patients with oral cancer when comparisons are made with healthy patients and patients with other oral diseases.

REFERENCES

• Brown, A.M.; Lally, E.T.; Frankel, A.; Harwick, R.; Davis, L.W.; and Rominger, C.J. (1975): The Association of the IgA Levels of Serum and Whole Saliva with the Progression of Oral Cancer, Cancer 35:1154-1162.[CrossRef][Medline] [Order article via Infotrieve]
• Guest, G.F. and Winters, W.D. (1979): Sensitivity of Human Oral Tumor Cells to Human Adenovirus, J Dent Res 58:1815-1823.[Abstract/Free Full Text]
• Kumari, T.V.; Shanmugam, J.; Prabla, B.; and Vasude-Van, D.M. (1982): Prevalence of Antibodies Against Herpes Simplex and Adenovirus in Oral and Cervical Patients - A Preliminary Report, Ind J Med Res 75:590-592.[Medline] [Order article via Infotrieve]
• Lehner, T.; Wilton, J.M.; Shillitoe, E.J.; and Ivanyi, L. (1973): Cell-Mediated Immunity and Antibodies to Herpesvirus hominis Type 1 in Oral Leukoplakia and Carcinoma, Br J Cancer 27:351-361.[Medline] [Order article via Infotrieve]
• Lesourd, B. and Winters, W.D. (1982): Specificity of Immune Responses to Skin Test Antigens Following Repeated Multiple Antigen Skin Tests in Normal Individuals, Clin Exp Immunol 50:635-643.[Medline] [Order article via Infotrieve]
• McGhee, J.R.; Michalek, S.M.; and Cassell, G.H. (1982): Dental Microbiology. Philadelphia: Harper & Row, p. 353.
• Russell, A.L. (1956): A System of Classification and Scoring for Prevalence Surveys of Periodontal Disease, J Dent Res 35:350-357.[Free Full Text]
• Scully, C. (1982): The Immunology of Cancer of the Head and Neck with Particular Reference to Oral Cancer, Oral Surg 53: 157-169.[CrossRef][Medline] [Order article via Infotrieve]
• Shillitoe, E.J.; Greenspan, D.; Greenspan, J.S.; and Silverman, S. (1983): Immunoglobulin Class of Antibody to Herpes Simplex Virus in Patients with Oral Cancer, Cancer 51: 65-71.[CrossRef][Medline] [Order article via Infotrieve]
• Shillitoe, E.J. and Silverman, S. (1979): Oral Cancer and Herpes Simplex Virus - A Review, Oral Surg 48:216-224.[CrossRef][Medline] [Order article via Infotrieve]
• Singh, G.; Rao, M.V.S.; and Rajvanshi, V.S. (1974): Neutralizing Antibodies to Adenoviruses in Patients with Carcinoma of the Oral Cavity and Control Individuals, Ind J Med Res 62: 254-257.[Medline] [Order article via Infotrieve]
• Smith, K.O. and Kennell, W.L. (1981): Differentiation of Members of the Human Herpesviridae Family by Radioimmunoassay, Infect Immun 33:491-497.[Abstract/Free Full Text]
• Winters, W.D. (1979): Human Adenovirus Antibody in Sera of Normal and Tumor-Bearing Dogs, Vet Rec 105:216-220.[Abstract]
• Winters, W.D. and Guest, G.F. (1979): Adenovirus Infections of Human Oral Tumor Cells, IADR Progr & Abst 58: No. 907.
• Winters, W.D. and Harris, S.C. (1982): Interferon Induction in Healthy and Tumor-Bearing Dogs by Cell Walls of Mycobacterium bovis Strain Bacille Calmette-Guérin, Am J Vet Res 43: 1232-1237.[Medline] [Order article via Infotrieve]
• Winters, W.D. and Lamm, D.L. (1981): Antibody Responses to Bacillus Calmette-Guérin During Immunotherapy in Bladder Cancer Patients, Cancer Res 41:2672-2676.[Abstract/Free Full Text]
• Winters, W.D. and Young, R.J. (1980): Incomplete Human Adenovirus Replication in Canine Tumor Cells and Serological Evidence of Infections in Tumor-Bearing Pets, J Comp Pathol 90:197-207.[CrossRef][Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 63, No. 11, 1306-1309 (1984)
DOI: 10.1177/00220345840630111101


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				W.D. Winters, G.F. Guest, and J.T. McAnear Letters to the Editor Journal of Dental Research, June 1, 1985; 64(6): 944 - 944. [PDF]

				Letters to the Editor Journal of Dental Research, June 1, 1985; 64(6): 944 - 944. [PDF]

This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Winters, W.D. Articles by McAnear, J.T. Search for Related Content PubMed PubMed Citation Articles by Winters, W.D. Articles by McAnear, J.T. Social Bookmarking                         What's this?