Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
Journal of Dental Research
This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Mason, J.D.
Right arrow Articles by Yukna, R.A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mason, J.D.
Right arrow Articles by Yukna, R.A.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Local Immunoglobulin Synthesis in Juvenile Periodontitis: Initial Findings

J.D. Mason

Department of Periodontics

J.J. Thompson

Microbiology & Immunology, Louisiana State University School of Dentistry, 1100 Florida Avenue, New Orleans, Louisiana 70119

R.A. Yukna

Department of Periodontics

An electro-immunoassay technique was used to determine simultaneously immunoglobulin G (IgG) and albumin concentrations in serum and extracts of gingival tissue comprising the pocket wall. Assays of samples obtained from seven patients with juvenile periodontitis (mean age, 18 years) indicated that local synthesis accounted for 72% of the IgG found in the gingiva.

REFERENCES

  • Baer, P.N. (1971): The Case for Periodontosis as a Clinical Entity, J Periodontol 42:516-519.[Medline] [Order article via Infotrieve]
  • Bock, E. and Axelsen, N.H. (1983): Partial Antigenic Identity, Scand J Immunol 17 (Suppl 10):183-187.[Medline] [Order article via Infotrieve]
  • Berglund, S. (1971): Immunoglobulins in Human Gingiva with Specificity for Oral Bacteria, J Periodontol 42:546-551.[Medline] [Order article via Infotrieve]
  • Bradford, M.M. (1976): A Rapid and Sensitive Method for the Quantification of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding, Anal Biochem 72:248-254.[CrossRef][Medline] [Order article via Infotrieve]
  • Brandtzaeg, P. (1966): Local Factors of Resistance in the Gingival Area, J Periodont Res 1:19-42.[CrossRef][Medline] [Order article via Infotrieve]
  • Brandtzaeg, P. (1972): Local Formation and Transport of Immunoglobulins Related to the Oral Cavity. In: Host Resistance to Commensal Bacteria, T. MacPhee, Ed., Edinburgh: Churchill Livingstone, pp. 116-150.
  • Brandtzaeg, P. (1975): Immunoglobulin Systems of Oral Mucosa and Saliva. In: Oral Mucosa in Health and Disease, A.E. Dolby, Ed., Oxford: Blackwell Scientific Publications, pp. 137-213.
  • Brandtzaeg, P. and Kraus, F.W. (1965): Autoimmunity and Periodontal Disease, Odontol Tidskr 73:281-393.[Medline] [Order article via Infotrieve]
  • Carvel, R.I.; Halperin, V.; and Wallace, J.H. (1973): Immunological Studies in Chronic Severe Alveolar Resorptive Disease: A Report of Two Young Female Patients, J Periodontol 44:25-34.[Medline] [Order article via Infotrieve]
  • Friedman, S.A.; Farber, P.A.; and Salkin, L.M. (1976): Histopathology of Juvenile Periodontitis. I. Surface Morphology of Inflammatory Cells, IADR Progr & Abst 55: No. 788.
  • Gebhard, J.D.; Newman, J.T.; Matthews, J.L.; Hurt, W.C.; and Stone, M.J. (1982): Immunopathology of Periodontal Disease. II. Immunofluorescent Studies of the Localized Immune Response in Periodontitis and Juvenile Periodontitis, JPeriodontol 53:239-244.[Medline] [Order article via Infotrieve]
  • Gottlieb, B. (1946): The New Concept of Periodontoclasia, J Periodontol 17:7-23.
  • Gross, A.; Setterstrom, J.A.; D'Alessandro, S.M.; and Van Swol, R.L. (1979): Immunoglobulins in Periodontal Tissues. I. Concentrations of Immunoglobulins in Normal and Inflamed Gingiva, J Periodontol 50:581-585.[Medline] [Order article via Infotrieve]
  • Johnson, R.J.; Matthews, J.L.; Stone, M.J.; Hurt, W.C.; and Newman, J.T. (1980): Immunopathology of Periodontal Disease. I. Immunologic Profiles in Periodontitis and Juvenile Periodontitis, J Periodontol 51:705-712.[Medline] [Order article via Infotrieve]
  • Kaslick, R.S.; Chasens, A.I.; Bressman, E.; Lazzara, R.; and Egitto, J. (1971): Investigation of Periodontosis with Periodontitis: Ultramicroanalysis of Gingival Fluid, Gross Examination of the Periodontal Ligament and Approach to Treatment, J Periodontol 42:428-434.[Medline] [Order article via Infotrieve]
  • Kaslick, R.S.; West, T.L.; Singh, S.M.; and Chasens, A.I. (1980): Serum Immunoglobulins in Periodontosis Patients, J Periodontol 51:343-344.[Medline] [Order article via Infotrieve]
  • Lally, E.T.; Bachni, P.C.; and McArthur, W.P. (1980): Local Immunoglobulin Synthesis in Periodontal Disease, J Periodont Res 15:159-164.[CrossRef][Medline] [Order article via Infotrieve]
  • Lehner, T. (1975): Immunological Aspects of Dental Caries and Periodontal Disease, Br Med Bull 31:125-130.[Free Full Text]
  • Lehner, T.; Wilton, J.M.; Ivanyi, L.; and Manson, J.D. (1974): Immunological Aspects of Juvenile Periodontitis (Periodontosis), J Periodont Res 9:261-272.[CrossRef][Medline] [Order article via Infotrieve]
  • Lovelace, B.M.; Thompson, J.J.; and Yukna, R.A. (1982): Evidence for Local Immunoglobulin Synthesis in Periodontitis, J Periodontol 53:626-630.[Medline] [Order article via Infotrieve]
  • Manson, J.D. and Lehner, T.: Clinical Features of Juvenile Periodontitis (Periodontosis), J Periodontol 45:636-640.
  • Orban, B. and Weinmann, J.P. (1942): Diffuse Atrophy of the Alveolar Bone (Periodontosis), J Periodontol 13:31-45.
  • Thonard, J.C. and Dalbow, M.H. (1965): Local Cellular Antibodies. I. Plaque Formation by Sensitized Oral Mucosal Cells from Conventional Animals, J Immunol 95:209-213.[Abstract/Free Full Text]
  • Tourtellotte, W.W.: What is Multiple Sclerosis? Laboratory Criteria for Diagnosis. In: Multiple Sclerosis Research, A.N. Davidson, Ed., New York, NY: Elsevier Scientific Publishing Co., 1975, pp. 9-26.
  • Tourtellotte, W.W.; Tavolato, B.; Parker, J.A.; and Comiso, P. (1971): Cerebrospinal Fluid Electroimmunodiffusion, Arch Neurol 25:345-350.[Abstract/Free Full Text]
  • Van Swol, R.L.; Gross, A.; Setterstrom, J.A.; and D'Allessandro, S.M. (1980): Immunoglobulins in Periodontal Tissues. II. Concentrations of Immunoglobulins in Granulation Tissue from Pockets of Periodontosis and Periodontitis Patients, J Periodontol 51:20-24.[Medline] [Order article via Infotrieve]
  • Waerhaug, J. (1976): Subgingival Plaque and Loss of Attachment in Periodontosis as Observed in Autopsy Material, J Periodontol 47:636-642.[Medline] [Order article via Infotrieve]
  • Waerhaug, J. (1977): Subgingival Plaque and Loss of Attachment in Periodontosis as Evaluated on Extracted Teeth, J Periodontol 48:125-130.[Medline] [Order article via Infotrieve]
  • Waldrop, T.C.; Mackler, B.F.; Schur, P.; and Killoy, W. (1981a): Immunologic Study of Human Periodontosis (Juvenile Periodontitis), J Periodontol 52:8-15.[Medline] [Order article via Infotrieve]
  • Waldrop, T.C.; Mackler, B.F.; and Schur, P. (1981b): IgG and IgG Subclasses in Human Periodontosis (Juvenile Periodontitis), J Periodontol 52:96-98.[Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 63, No. 10, 1211-1213 (1984)
DOI: 10.1177/00220345840630100801


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?



This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Mason, J.D.
Right arrow Articles by Yukna, R.A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mason, J.D.
Right arrow Articles by Yukna, R.A.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?