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Biologic Evaluation of a Silver-Copper-Germanium Dental Casting Alloy and a Gold-Germanium Coating Alloy

Department of Restorative Dentistry

A.I. Hamilton

Department of Restorative Dentistry

L. Sbordone

Department of Periodontics, University of Washington, School of Dentistry, Seattle, Washington 98195

An Ag-Cu-Ge alloy and an Au-Ge alloy were evaluated for their hemolytic effect on rabbit blood, cytotoxicity to -L fibrosarcoma cells, and allergenic effect on guinea pigs. Neither alloy evoked a significant hemolytic response; cytotoxicity, and that of pure germanium, was no greater than that of ZOE cement; and, on the basis of the guinea pig response, the potential human allergenic response was considered to be Grade I (weak) and Grade II (mild), respectively.

REFERENCES

• YOUDELIS, W.V. and YOUDELIS, R.A.: Silver-Copper-Germanium Alloys, J Can Dent Assoc 47:101-106, 1981. 2. Association Reports: Council on Dental Materials and Devices, JADA 99:697-698, 1979.
• American National Standards Institute/American Dental Association Document No. 41 for Recommended Standard Practices for Biological Evaluation of Dental Materials, Chicago, Illinois: American Dental Association, 1979, pp. 1-86.
• Commission on Dental Materials, Instruments, Equipment, and Therapeutics and the Commission on Dental Research, FDI/ ADA, International Conference: Standardization of Methods for Evaluation of Tissue Reactions to Dental Restorative Procedures, Materials and Therapeutics, Int Dent J 20:472-532, 1970.[Medline] [Order article via Infotrieve]
• Stanford, J.W.: Recommended Standard Practices for Biological Evaluation of Dental Materials: Federation Dentaire Internationale, Commission on Dental Materials, Instruments, Equipment, and Therapeutics, Int Dent J 30:140-188, 1980.[Medline] [Order article via Infotrieve]
• Autian, J.: Toxicological Evaluation of Biomaterials: Primary Acute Toxicity Screening Program, Artif Organs 1:53-60, 1977.[Medline] [Order article via Infotrieve]
• Council on Dental Materials and Devices: Certification Programs for Dental Materials and Devices, JADA 96:124-134, 1978.
• Sims, T.; Clagett, J.A.; and Page, R.C.: Effects of Cell Concentration and Exogenous Prostaglandin on the Interaction and Responsiveness of Human Peripheral Blood Leukocytes, Clin Immunol Immunopathol 12:150-161, 1979.[CrossRef][Medline] [Order article via Infotrieve]
• Spangberg, L.: Kinetic and Quantitative Evaluation of Material Cytotoxicity in vitro, Oral Surg 35:389-400 1973.[CrossRef][Medline] [Order article via Infotrieve]
• Townsend, J.D.; Hamilton, A.I.; and Sbordone, L.: Biologic Evaluation of an Amalgam Containing Indium and Two Germanium-containing Alloys for Cast Prostheses, AADR Progr & Abst 62: No. 472, 1983.
• Magnusson, B. and Kligman, A.M.: The Identification of Contact Allergens by Animal Assay. The Guinea Pig Maximization Test, J Invest Dermatol 52:268-276, 1969.[Medline] [Order article via Infotrieve]
• Black, J.: Biological Performance of Materials. In: Biomedical Engineering and Instrumentation Series, Vol. 8, Plonsky, R. and Katz, J.L., Eds., New York and Basel: Marcel Dekker, Inc., 1981, pp. 195-200.
• Dhal, B.L. and Orstavik, J.: Cytotoxicity of Temporary Crown and Bridge Materials, J Oral Rehabil 3:341-347, 1976.[CrossRef][Medline] [Order article via Infotrieve]
• Browne, R.M. and Tyas, M.J.: Biological Testing of Dental Restorative Materials in vitro - A Review, J Oral Rehabil 6: 365-374, 1979.[CrossRef][Medline] [Order article via Infotrieve]
• Hensten-Pettersen, A. and Helgeland, K.: Evaluation of Biologic Effects of Dental Materials Using Four Different Cell Culture Techniques, Scand J Dent Res 85:291-296, 1977.[Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 62, No. 8, 899-903 (1983)
DOI: 10.1177/00220345830620081001


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Townsend, J.D. Articles by Sbordone, L. Search for Related Content PubMed PubMed Citation Articles by Townsend, J.D. Articles by Sbordone, L. Social Bookmarking                         What's this?