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Journal of Dental Research
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Rat Caries Assay of Reference Foods and Sugar-containing Snacks

J.M. Navia

Institute of Dental Research and Department of Nutrition Sciences, University of Alabama School of Dentistry and School of Community and Allied Health, University of Alabama, Birmingham, Alabama 35294

H. Lopez

Institute of Dental Research and Department of Nutrition Sciences, University of Alabama School of Dentistry and School of Community and Allied Health, University of Alabama, Birmingham, Alabama 35294

Using standard reference snack foods, we tested a method, using rats fed in a programed feeding machine, to evaluate the caries-promoting properties of foods. Results, which were expressed in relation to a control food, indicate that the method distinguished differences in caries potential among a number of different snack foods. Buccal and sulcal caries scores of rats fed snack foods varied in their responses. A gel diet used to provide essential nutrients for the rat growth in this approach contributed minimally to the caries response which was related principally to the food being tested.

REFERENCES

  • Navia, J.M.: Experimental Dental Caries. In: Animal Models in Dental Research, J.M. Navia, Ed., University, Alabama: University of Alabama Press, 1977, pp. 257-297.
  • Navia, J.M.: Experimental and Husbandry Procedures in Rat Caries Research. In: Animal Models in Cariology, J.M. Tanzer, Ed., Sp. Supp., Microbiol Abstr, 1981, pp. 77-87.
  • Navia, J.M.: Perinatal Nutritional Influences on Experimental Rat Caries. In: Animal Models in Cariology, J.M. Tanzer, Ed., Sp. Supp., Microbiol Abstr, 1981, pp. 319-328.
  • Navia, J.M.: Evaluation of Nutritional and Dietary Factors that Modify Animal Caries, J Dent Res 49:1213-1227, 1970.[Free Full Text]
  • Konig, K.G.; Schmid, P.; and Schmid, R.: An Apparatus for Frequency-controlled Feeding of Small Rodents and Its Use in Dental Caries Experiments, Arch Oral Biol 13:13-26, 1968.[CrossRef][Medline] [Order article via Infotrieve]
  • Bowen, W.H.; Amsbaugh, S.M.; Monell-Torrens, S.; Brunelle, M.S.; Kuzmiak-Jones, H.; and Cole, M.F.: A Method to Assess Cariogenic Potential of Foodstuffs, JADA 100:677-681,1980.
  • Navia, J.M.: Models for Food Cariogenicity Testing: Report of a Collaborative Study Using Animal Models. In: Foods, Nutrition, and Dental Health, J.J. Hefferren, W.A. Ayer, and H.M. Koehler, Eds., Park Forest South, Illinois: Pathotox, 1981, pp. 1-13.
  • Firestone, A.R.; Schmid, R.; and Muhlemann, H.R.: Cariogenic Effects of Cooked Wheat Starch Alone or With Sucrose and Frequency-controlled Feedings in Rats, Arch Oral Biol 27:759-763, 1982.[CrossRef][Medline] [Order article via Infotrieve]
  • Stephan, R.M.: Effects of Different Types of Human Foods on Dental Health, J Dent Res 45:1551-1561, 1966.[Free Full Text]
  • Leveille, G.A.: Michigan State University Reference Foods. In: Foods, Nutrition, and Dental Health, J.J. Hefferren, W.A. Ayer, H.M. Koehler, Eds., Park Forest South, Illinois; Pathotox, 1981, pp. 43-53.
  • Navia, J.M.; Lopez, H.; and Harris, R.S.: Purified Diet for Dental Caries Research, J Nutr 97:133-140, 1969.[Abstract/Free Full Text]
  • Keyes, P.H.: Dental Caries in the Molar Teeth of Rats. II. A Method for Diagnosing and Scoring Several Types of Lesions Simultaneously, J Dent Res 37:1088-1099, 1958.[Free Full Text]
  • Duncan, D.B.: Multiple Range and Multiple F Tests, Biometrics 11:1-42, 1955.[Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 62, No. 8, 893-898 (1983)
DOI: 10.1177/00220345830620080901


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This Article
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Right arrow Articles by Navia, J.M.
Right arrow Articles by Lopez, H.
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Right arrow Articles by Navia, J.M.
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What's this?