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Journal of Dental Research
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Ultrastructural Characteristics of Progenitor Cell Populations in the Periodontal Ligament

T.R.L. Gould

Division of Periodontics, Faculty of Dentistry, University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, Canada V6T IZ7

Electron microscope radio-autography was used in an attempt to identify any relationship between the location and degree of differentiation of progenitor cells in the periodontal ligament (PDL). Ligament fibroblasts were classified on the basis of their nuclear/ cytoplasmic ratio and their distance to the closest blood vessel measured. It was determined that an undifferentiated paravascular progenitor cell population exists, and that the PDL also contains progenitor cells showing a range of cytodifferentiation.

REFERENCES

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  • Gould, T.R.L.; Melcher, A.H.; and Brunette, D.M.: Migration and Division of Progenitor Cell Populations in Periodontal Ligament after Wounding, J Periodont Res 15:20-42, 1980.[CrossRef][Medline] [Order article via Infotrieve]
  • McCulloch, C.A.G. and Melcher, A.H.: Variations in Cell Density and Labeling Index in Mouse Periodontal Ligament, IADR Progr & Abst 60:No. 563, 1981.
  • Melcher, A.H.: The Connective Tissues of the Periodontium. In: Biology of the Periodontium, Melcher, A.H. and Bowen, W.H., Eds., New York: Academic Press, 1969, pp. 167-343.
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  • Leblond, C.P. and Cheng, H.: Identification of Stem Cells in the Small Intestine of the Mouse. In: Stem Cells in Renewing Cell Populations, Cairnie, A.B., Lala, P.K., and Osmond, D.G., Eds., New York: Academic Press, 1976, pp. 7-31.
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  • Brunette, D.M.; Melcher, A.H.; and Moe, H.K.: Culture and Origin of Epithelium-like and Fibroblast-like Cells from Porcine Periodontal Ligament Explants and Cell Suspensions, Arch Oral Biol 21:393-400, 1976.[CrossRef][Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 62, No. 8, 873-876 (1983)
DOI: 10.1177/00220345830620080401


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This article has been cited by other articles:


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M.J. Somerman, S.Y. Archer, G.R. Imm, and R.A. Foster
A Comparative Study of Human Periodontal Ligament Cells and Gingival Fibroblasts in vitro
Journal of Dental Research, January 1, 1988; 67(1): 66 - 70.
[Abstract] [PDF]


This Article
Right arrow Abstract Freely available
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Right arrow Alert me when this article is cited
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What's this?