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Biosynthesis of 17β-estradiol and Its Binding to Specific Receptors in Human Gingiva
J. Vittek
Departments of Medicine and Dentistry, New York Medical College, Valhalla, New York 10595
G.G. Gordon
Departments of Medicine and Dentistry, New York Medical College, Valhalla, New York 10595
P.R. Munnangi
Departments of Medicine and Dentistry, New York Medical College, Valhalla, New York 10595
S.C. Rappaport
Departments of Medicine and Dentistry, New York Medical College, Valhalla, New York 10595
A.L. Southren
Departments of Medicine and Dentistry, New York Medical College, Valhalla, New York 10595
An increased biosynthesis of 17β-estradiol was found by microsomes obtained from the inflamed human gingivae when compared to those from healthy and hyperplastic tissues. In contrast, binding of estradiol to cytoplasmic receptors was increased only in hyperplastic tissue and was independent of the amount of estradiol formed.
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Journal of Dental Research, Vol. 62, No. 3,
341-343 (1983)
DOI: 10.1177/00220345830620030701

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