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Changes in Protein Composition of Saliva from Radiation-induced Xerostomia Patients and Its Effect on Growth of Oral Streptococci
R.A. Cowman
Dental Research Unit, Miami Veterans Administration Medical Center, Miami, Florida 33125
S.S. Baron
Dental Research Unit, Miami Veterans Administration Medical Center, Miami, Florida 33125
A.H. Glassman
Dental Service, Miami Veterans Administration Medical Center, Miami, Florida 33125
M.E. Davis
Dental Service, Miami Veterans Administration Medical Center, Miami, Florida 33125
A.M. Strosberg
Dental Service, Miami Veterans Administration Medical Center, Miami, Florida 33125
Clarified and dialyzed mixed saliva-water rinses, obtained from patients receiving radiation treatment of the major salivary glands, exhibited quantitative reductions in total protein content and qualitative changes in protein composition. Radiation or post-radiation saliva preparations supported enhanced growth of Streptococcus mutans, but reduced growth of Streptococcus sanguis relative to growth on pretreatment saliva.
REFERENCES
- Shannon, I.L.; Starcke, E.N.; and Westcott, W.B.: Effect of Radiotherapy on Whole Saliva Flow, J Dent Res 56: 693, 1977.[Free Full Text]
- Brown, L.R.; Dreizen, S.; Rider, L.J.; and Johnston, D.A.: The Effect of Radiation-Induced Xerostomia on Saliva and Serum Lysozyme and Immunoglobulin Levels, Oral Surg 41:83-92, 1976.[CrossRef][Medline]
[Order article via Infotrieve]
- Dreizen, S.; Brown, L.R.; Handler, S.; and Levy, B.M.: Radiation Induced Xerostomia in Cancer Patients. Effect on Salivary and Serum Electrolytes, Cancer 38:273-278, 1976.[CrossRef][Medline]
[Order article via Infotrieve]
- Brown, L.R.; Dreizen, S.; Daly, T.E.; Drane, J.B.; Handler, S.; Riggan, L.J.; and Johnston, D.A.: Interrelations of Oral Microorganisms, Immunoglobulins, and Dental Caries Following Radiotherapy, J Dent Res 57:882-893, 1978.[Abstract/Free Full Text]
- Dreizen, S.; Brown, L.R.; Daly, T.E.; and Drane, J.B.: Prevention of Xerostomia-related Dental Caries in Irradiated Cancer Patients, JDent Res 56:99-104, 1977.
- Llory, H.; Dammron, A.; Gioanni, M.; and Frank, R.J.: Some Population Changes in Oral Anaerobic Microorganisms, Streptococcus mutans and Yeasts Following Irradiation of the Salivary Glands, Caries Res 6:298-311, 1972.[Medline]
[Order article via Infotrieve]
- Brown, L.R.; Dreizen, S.; Handler, S.; and Johnston, D.A.: Effect of Radiation-induced Xerostomia on Human Oral Microflora, Dent Res 54:740-750, 1975.
- Dreizen, S. and Brown, L.R.: Xerostomia and Dental Caries. In: Proceedings: Microbial Aspects of Dental Caries, Vol. 1, Stiles, Loesche, and O'Brien, Eds., Sp. Suppl., Microbiology Abstracts, 1976, pp. 263-273.
- Brown, L.R.; Dreizen, S.; and Handler, S.: Effects of Selected Caries Preventive Regimens on Microbial Changes Following Irradiation-Induced Xerostomia in Cancer Patients. In: Proceedings: Microbial Aspects of Dental Caries, Vol. 1, Stiles, Loesche, and O'Brien, Eds., Sp. Suppl., Microbiology Abstracts, 1976, pp. 275-290.
- Mandel, I.D.: Nonimmunologic Aspects of Caries Resistance, J Dent Res 55:C22-C31, 1976.[Free Full Text]
- Cowman, R.A.; Fitzgerald, R.J.; Perrella, M.M.; and Cornell, A.H.: Human Saliva as a Nitrogen Source for Oral Streptococci, Caries Res 11:1-8, 1977.[Medline]
[Order article via Infotrieve]
- Cowman, R.A.; Schaefer, S.J.; and Fitzgerald, R.J.: Specificity of Utilization of Human Salivary Proteins for Growth by Oral Streptococci, Caries Res 13:181-189, 1979.[Medline]
[Order article via Infotrieve]
- Cowman, R.A.; Baron, S.J.; and Fitzgerald, R.J.: Utilization of Hydroxyapatite Adsorbable Salivary Proteins as Growth Substrates for Plaque-forming Oral Streptococci, J Dent Res 60:1803-1808, 1981.[Abstract/Free Full Text]
- Cowman, R.A.; Schaeffer, S.J.; Fitzgerald, R.J.; Rosner, D.; Shklair, I.L.; and Walter, R.G.: Differential Utilization of Proteins in Saliva from Caries-active and Caries-free Subjects as Growth Substrates by Plaque-forming Streptococci, J Dent Res 58:2019-2027, 1979.[Abstract/Free Full Text]
- Cowman, R.A.; Perrella, M.M.; and Fitzgerald, R.J.: Influence of Incubation Atmosphere on Growth and Amino Acid Requirements of Streptococcus mutans, Appl Microbiol 27:86-92, 1974.[Medline]
[Order article via Infotrieve]
- Dubois, M.; Gilles, K.A.; Hamilton, J.K.; Rebers, P.A.; and Smith, F.: Colorimetric Method for the Determination of Sugars and Related Substances, Anal Chem 28: 350-356,1956.
- Iwamoto, Y.; Tsunemitsu, A.; and Okuda, K.: Iodide Peroxidase Activity in the Antibacterial System in Human Parotid and Submandibular Saliva, J Dent Res 51:877, 1972.[Free Full Text]
- Rosenmund, H. and Kaczmarek, M.J.: Isolation and Characterization of Isozymes of Human Salivary and Pancreatic
-Amylase, Clin Chim Acta 71:185-189, 1976.[CrossRef][Medline]
[Order article via Infotrieve] - Mandel, I.D. and Wotman, S.: The Salivary Secretions in Health and Disease, Oral Sci Rev 8:24-47, 1976.
- Sodicoff, M.; Pratt, N.E.; Trepper, P.; Sholley, M.M.; and Hoffenberg, S.: Effects of X-Irradiation on the Resultant Inanition of Amylase Content of the Rat Parotid Gland, Arch Oral Biol 22:261-267, 1977.[CrossRef][Medline]
[Order article via Infotrieve]
- Thomas, E.L.: Myeloperoxidase, Hydrogen Peroxide, Chloride Antimicrobial System: Nitrogen-Chloride Derivatives of Bacterial Components in Bactericidal Action against Escherichia coli, Infect Immun 23:522-531, 1979.[Abstract/Free Full Text]
- Hager, L.P.; Morris, D.R.; Brown, S.F.; and Eberwein, H.: Chloroperoxidase. II. Utilization of Halogen Anions, J Biol Chem 241:1769-1777,1966.[Abstract/Free Full Text]
- Cowman, R.A. and Schaefer, S.J.: Amino Acid Requirements and Human Saliva as a Nitrogen Source for Streptococcus salivarius and Streptococcus mitior, J Dent Res 57:48, 1978.[Free Full Text]
Journal of Dental Research, Vol. 62, No. 3,
336-340 (1983)
DOI: 10.1177/00220345830620030601

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