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Plasma Beta-Endorphin-like Immunoreactivity, Pain and Anxiety Following Administration of Placebo in Oral Surgery Patients
K.M. Hargreaves
Neurobiology and Anesthesiology Branch, National Institute of Dental Research, NIH, Bethesda, MD 20205, Georgetown University School of Dentistry, Washington, DC 20007
R.A. Dionne
Neurobiology and Anesthesiology Branch, National Institute of Dental Research, NIH, Bethesda, MD 20205
G.P. Mueller
Department of Physiology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814
Plasma beta-endorphin was measured in patients undergoing a stressful procedure, the removal of impacted third molars. In patients reporting little pain, endorphin levels increased significantly during surgery, whereas patients reporting pain and anxiety showed little increase in endorphin levels.
REFERENCES
- Rogers, E. and Vilkin, B.: Diurnal Variation in Sensory and Pain Thresholds Correlated with Mood States, J Clin Psychiatry 39:431-433, 1978.[Medline]
[Order article via Infotrieve]
- Dent, R.: Diurnal Rhythm of Plasma Immunoreactive Beta-Endorphin and its Relationship to Sleep Stages and Plasma Rhythms of Cortisol and Prolactin, J Clin Endocrinol Metab 52:942-947, 1981.[Abstract/Free Full Text]
- Glynn, C. and Lloyd, J.: The Diurnal Variation in the Perception of Pain, Proc R Soc Med 69:369-372, 1976.[Medline]
[Order article via Infotrieve]
- Gjessing, J. and Tomlin, P.: Patterns of Post-Operative Pain, Anaesthesia 43:624, 1979.
- Denko, C.: Beta-Endorphin Levels Lower in Arthritis Patients, JAMA 246:203, 1981.[Abstract/Free Full Text]
- Rossier, J.: Foot-shock Induced Stress Increases β-Endorphin Levels in Blood But Not Brain, Nature 270:618-620, 1977.[CrossRef][Medline]
[Order article via Infotrieve]
- Willer, J.; Dehen, H.; and Cambier, J.: Stress-induced Analgesia in Humans: Endogenous Opiates and Naloxone-Reversible Depression of Pain Reflexes, Science 212:689-691, 1981.[Abstract/Free Full Text]
- Thomas, T.; Fletcher, J.; and Hill, R.: Influence of Medication, Pain and Progress in Labour on Plasma B-EP-LI, Br J Anaesth 54:401-408, 1981.[CrossRef]
- Steinbrook, R.; Carr, D.; and Datta, S.: Dissociation of Plasma and CSF B-End-LI Levels During Pregnancy and Parturition, Anesth Analg 61:893-897, 1982.[Abstract/Free Full Text]
- Dubois, M.; Pickar, D.; and Cohen, M.: Surgical Stress in Humans is Accompanied by an Increase in Plasma B-End-LI, Life Sci 29:1249-1254, 1981.[CrossRef][Medline]
[Order article via Infotrieve]
- Dubois, M.; Pickar, D.; and Cohen, M.: Effect of Fentanyl on the Response of Plasma Beta-Endorphin Immunoreactivity to Surgery, Anesthesiology 57:468-472, 1982.[Medline]
[Order article via Infotrieve]
- Cohen, M.; Pickar, D.; Dubois, M.; and Bunney, W.: Stress Induced Plasma Endorphin Immunoreactivity May Predict Post-Operative Morphine Usage, Psychiatry Reg 6:7-12, 1982.[CrossRef]
- Kraynack, B. and Gintautas, J.: Naloxone: Analeptic Action Unrelated to Opiate Receptor Antagonism?, Anesthesiology 56:251-253, 1982.[Medline]
[Order article via Infotrieve]
- Berkowitz, B.; Ngai, S.; and Finck, 0.: Nitrous Oxide Analgesia: Resemblance to Opiate Action, Science 194:967-969, 1976.[Abstract/Free Full Text]
- Finck, 0.; Ngai, S.; and Berkowitz, B.: Antagonism of General Anesthesia by Naloxone in the Rat, Anesthesiology 46:241-244, 1977.[Medline]
[Order article via Infotrieve]
- Gracely, R.: Psychophysical Assessment of Human Pain. In: Advances in Pain Research and Therapy, Vol. 3, Bonica, J., Ed., New York: Raven Press, 1979, pp. 805-821.
- Dionne, R.; Sisk, A.; Fox, P.; Wirdzek, P.; Gracely, R.; and Dubner, R.: Suppression of Post-operative Pain by Pre-operative Administration of Flurbiprofen in Comparison to Acetaminophen and Oxycodone Plus Acetaminophen, Curr Ther Res 34:15-29, 1983.
- Goldstein, D.; Dionne, R.; Sweet, J.; Gracely, R.; Brewer, B.; Gregg, R.; and Keiser, H.: Circulating Plasma Catecholamine, Cortisol, Lipid and Psychological Responses to a Real-Life Stress (Third Molar Extraction): Effects of Diazepam Sedation and of Inclusion of Epinephrine with the Local Anesthetic, Psychosomatic Medicine 44:259-272, 1982.[Abstract/Free Full Text]
- Sapun, D.; Farah, J.; and Mueller, G.: Evidence that a Serotonergic Mechanism Stimulates the Secretion of Pituitary B-Endorphin-like Immunoreactivity in the Rat, Endocrinology 109:421-426, 1982.
- Hunter, W. and Greenwood, F.: Preparation of Iodine-131 Labeled Human Growth Hormone of High Specific Activity, Nature 194:495-498, 1962.[CrossRef][Medline]
[Order article via Infotrieve]
Journal of Dental Research, Vol. 62, No. 11,
1170-1173 (1983)
DOI: 10.1177/00220345830620111601
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R. Matejec, R. Ruwoldt, R.-H. Bodeker, G. Hempelmann, and H. Teschemacher
Release of {beta}-Endorphin Immunoreactive Material Under Perioperative Conditions into Blood or Cerebrospinal Fluid: Significance for Postoperative Pain?
Anesth. Analg.,
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96(2):
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