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Action of Drugs on Liposomes with Varying Charges

School of Dentistry, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113, Japan

Y. Kadoma

Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, 2-3-10 Surugadai, Kanda, Chiyoda-ku, Tokyo 101, Japan

E. Masuhara

The effects of 12 amphipathic compounds-such as aromatic and aliphatic carboxylic acids, amines, imines, nitrogen-substituted derivatives, and aldehydes-on multilamellar liposomes with varying charges were monitored in biological systems. The stabilization-lysis action of amphipathic compounds on liposomes was influenced by either the electrostatic repulsion or the attraction force between these compounds and liposomes.

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Journal of Dental Research, Vol. 62, No. 1, 65-68 (1983)
DOI: 10.1177/00220345830620011501


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This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Fujisawa, S. Articles by Masuhara, E. Search for Related Content PubMed PubMed Citation Articles by Fujisawa, S. Articles by Masuhara, E. Social Bookmarking                         What's this?