|
Sign In to gain access to subscriptions and/or personal tools.
|
The Effects of Plasma and Salivary Constituents on Dentin Permeability
D.H. Pashley
Departments of Oral Biology and Physiology, Medical College of Georgia, Augusta, Georgia 30901
R. Nelson
Departments of Oral Biology and Physiology, Medical College of Georgia, Augusta, Georgia 30901
E.E. Kepler
Departments of Oral Biology and Physiology, Medical College of Georgia, Augusta, Georgia 30901
The experiments described in this report were designed to determine the possible influence of plasma and salivary constituents on dentin permeability, in vitro. The results indicate that plasma, serum, and whole (mixed) saliva are all capable of causing immediate reductions in dentin permeability. Individual plasma protein fractions and several different types of bacteria were also effective in reducing the ease with which fluid can move across dentin. These observations may provide a mechanism for the "spontaneous" reductions in dentin sensitivity seen by clinicians following periodontal therapy.
REFERENCES
- Blitzer, B.: A Consideration of the Possible Causes of Dental Hypersensitivity: Treatment by a Strontium Ion Dentifrice, Periodontics 5:318-321, 1967.[Medline]
[Order article via Infotrieve]
- Pusso-Carrasco, H.: Strontium Chloride Toothpaste- Effectiveness as Related to Duration of Use, Pharmacol Ther Dent 1:209-215, 1971.[Medline]
[Order article via Infotrieve]
- Hernandez, F.; Mohammed, C.; Shannon, I.; Volpe, A.; and King, W.: Clinical Study Evaluating the Desensitizing Effect and Duration of Two Commercially Available Dentifrices, J Periodontol 43:367-372, 1972.[Medline]
[Order article via Infotrieve]
- Uchida, A.; Wakano, Y.; Fukuyama, 0.; Miki, T.; Iwayama, Y.; and Okada, H.: Controlled Clinical Evaluation of a 10% Strontium Chloride Dentifrice in Treatment of Dentin Hypersensitivity Following Periodontal Surgery, J Periodontol 51:578-581, 1980.[Medline]
[Order article via Infotrieve]
- Brannstrom, M. and Astrom, M.: The Hydrodynamics of the Dentin: Its Possible Relationship to Dental Pain, Int Dent J 22:219-227, 1972.[Medline]
[Order article via Infotrieve]
- Greenhill, J.D. and Pashley, D.H.: The Effect of Desensitizing Agents on the Hydraulic Conductance of Human Dentin, in vitro, J Dent Res 60:686-698, 1981.[Abstract/Free Full Text]
- Michelich, V.; Pashley, D.H.; and Whitford, G.M.: Dentin Permeability: A Comparison of Functional versus Anatomical Tubular Radii, J Dent Res 57:1019-1024, 1978.[Abstract/Free Full Text]
- Brannstrom, M. and Garberoglio, R.: Occlusion of Dentinal Tubules Under Superficial Attrited Dentine, Scand Dent J 4:87-91, 1980.
- Michelich, V.; Schuster, G.S.; and Pashley, D.H.: Bacterial Penetration of Human Dentin, in vitro, J Dent Res 59:1398-1403,1980.[Abstract/Free Full Text]
- Spreter von Kreudenstein, Von Th.: Dentinstoffwechselstudien. I. Mitteilung. Uber den Dentinliquor, Dtsch Zahnaertztl Z 10:473-476, 1955.
- Haldi, J.; Wynn, W.; and Culpepper, W.D.: Dental Pulp Fluid, I. Relationship Between Dental Pulp Fluid and Blood Plasma in Protein, Glucose, and Inorganic Element Content, Arch Oral Biol 3:201-206, 1961.
- Haldi, J. and Wynn, W.: Protein Fractions of the Blood Plasma and Dental Pulp Fluid of the Dog, J Dent Res 42: 1217-1221,1963.[Free Full Text]
- Okamura, K.; Tsubakimoto, K.; Uobe, K.; Nishida, K.; and Tsutsui, M.: Serum Proteins and Secretory Component in Human Carious Dentin, J Dent Res 58:1127-1133, 1979.[Abstract/Free Full Text]
- Okamura, K.; Tanaka, A.; Kahehi, A.; Maeda, M.; and Tsutsui, M.: Plasma Components in Deep Lesions of Human Carious Dentin, J Dent Res 58:2010, 1979.[Free Full Text]
- Reeder, O.W.; Walton, R.E.; Livingston, M.J.; and Pashley, D.H.: Dentin Permeability: Determinants of Hydraulic Conductance, J Dent Res 57:187-193, 1978.[Abstract/Free Full Text]
- Schneyer, L.H.: Method for the Collection of Separate Submaxillary and Sublingual Salivas in Man, J Dent Res 34: 257-261, 1955.[Free Full Text]
- Lowry, O.H.; Rosebrough, N.H.; Farr, A.L.; and Randall, R.J.: Protein Measurement with the Folin Phenol Reagent, J Biol Chem 193:265-275, 1951.[Free Full Text]
- Daculsi, G.; Kerebel, B.; LeCabellec, M.T.; and Kerebel, L.M.: Qualitative and Quantitative Data on Arrested Caries in Dentin, Caries Res 13:190-202, 1979.[Medline]
[Order article via Infotrieve]
- Mendis, B.R.R.N. and Darling, A.I.: A Scanning Electron Microscope Microradiographic Study of Human Coronal Dentinal Tubules Related to Occlusal Attrition and Caries, Arch Oral Biol 24:725-733, 1979.[CrossRef][Medline]
[Order article via Infotrieve]
- Brodin, E.; Gazelius, B.; Lundberg, J.M.; and Olgart, L.: Substance P in Trigeminal Nerve Endings: Occurrence and Release, Acta Physiol Scand 111:501-504, 1981.[CrossRef][Medline]
[Order article via Infotrieve]
Journal of Dental Research, Vol. 61, No. 8,
978-981 (1982)
DOI: 10.1177/00220345820610081201
 CiteULike  Complore  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter What's this?
This article has been cited by other articles:
|
|
|
|
 
R.M. Love and H.F. Jenkinson
INVASION OF DENTINAL TUBULES BY ORAL BACTERIA
Critical Reviews in Oral Biology & Medicine,
March 1, 2002;
13(2):
171 - 183.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D.G. Gillam, N.J. Mordan, and H.N. Newman
The Dentin Disc Surface: A Plausible Model for Dentin Physiology and Dentin Sensitivity Evaluation
Advances in Dental Research,
November 1, 1997;
11(4):
487 - 501.
[Abstract]
[PDF]
|
|
|
|
|
|
|
M. Yoshiyama, Y. Noiri, K. Ozaki, A. Uchida, Y. Ishikawa, and H. Ishida
Transmission Electron Microscopic Characterization of Hypersensitive Human Radicular Dentin
Journal of Dental Research,
June 1, 1990;
69(6):
1293 - 1297.
[Abstract]
[PDF]
|
|
|
|
|
|
|
D.H. Pashley, S. Kalathoor, and D. Burnham
The Effects of Calcium Hydroxide on Dentin Permeability
Journal of Dental Research,
March 1, 1986;
65(3):
417 - 420.
[Abstract]
[PDF]
|
|
|
|
|
