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Neurotoxic Effects of Root Filling Materials on Rat Phrenic Nerve in vitro

Departments of Pedodontics

A. Røed

Department of Physiology and Biochemistry, Dental Faculty, University of Oslo

H. Aars

Department of Physiology and Biochemistry, Dental Faculty, University of Oslo

D. ørstavik

NIOM, Scandinavian Institute of Dental Materials, Oslo, Norway

Inhibitory effects of root filling materials on the conduction of action potentials evoked in rat phrenic nerves were evaluated in vitro. Endomethasone and N2 Normal completely and irreversibly inhibited conductance; ProcoSol caused complete but reversible inhibition; Kloroperka N-O caused total inhibition which was sometimes reversed; and AH26 and Diaket showed partial inhibition which was partially reversible.

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Journal of Dental Research, Vol. 61, No. 8, 1020-1023 (1982)
DOI: 10.1177/00220345820610080501


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