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Properties of Cysteine-containing Phosphoproteins from Human Submandibular-sublingual Saliva
J.P. Shomers
Department of Oral Biology, School of Dentistry, State University of New York at Buffalo, Buffalo, New York 14226
L.A. Tabak
Department of Oral Biology, School of Dentistry, State University of New York at Buffalo, Buffalo, New York 14226
M.J. Levine
Department of Oral Biology, School of Dentistry, State University of New York at Buffalo, Buffalo, New York 14226
I.D. Mandel
School of Dental and Oral Surgery, Columbia University, New York City, New York 10032
D.I. Hay
Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
Cysteine-containing phosphoproteins (CCP) similar to those found in human submandibular-sublingual saliva have also been detected in parotid saliva and tears suggesting a serous origin. No appreciable difference was found in salivary CCP concentrations between caries-susceptible and caries-resistant individuals. CCPadsorbed to hydroxyapatite, and this binding was due in part to phosphate residues. In addition, these molecules inhibited the transformation of dicalcium phosphate dihydrate, albeit to a lesser extent than statherin.
REFERENCES
- Shomers, J.P.; Tabak, L.A.; Levine, M.J.; Mandel, I.D.; and Ellison, S.A.: The Isolation of a Family of Cysteine-containing (Phospho) proteins from Human Submandibular-sublingual Saliva, J Dent Res, In press.
- Shomers, J.P.; Tabak, L.A.; Levine, M.J.; Mandel, I.D.; and Ellison, S.A.: Characterization of Cysteine-containing Phosphoproteins from Human Submandibular-sublingual Saliva, JDent Res, In press.
- Block, P. and Brotman, S.: A Method of Submaxillary Saliva Collection Without Cannulization, NY State Dent J 28:116-118,1962.
- Curby, W.A.: Device for Collection of Human Parotid Saliva, J Lab Clin Med 41:493-496, 1953.[Medline]
[Order article via Infotrieve]
- Herzberg, M.C.; Levine, M.J.; Ellison, S.A.; and Tabak, L.A.: Purification and Characterization of Monkey Salivary Mucin, J Biol Chem 254:1487-1494, 1979.[Abstract/Free Full Text]
- Bjerrum, O.J.; Ingild, A.; Lwenstein, H.; and Weeke, B.: Carbamylated Antibodies Used for Quantitation of Human IgG. In: A Manual of Quantitative Immunoelectrophoresis, Axelsen, N.H., Krøll, J., and Weeke, B., Eds., Scand J Immunol (Suppl. No. 1) 2:145-148, 1973.
- Bennick, A. and Cannon, M.: Quantitative Study of the Interaction of Salivary Acidic Proline-rich Proteins with Hydroxyapatite, Caries Res 12:159-169, 1978.[Medline]
[Order article via Infotrieve]
- Lowry, O.H.; Rosebrough, N.J.; Farr, A.L.; and Randall, R.J.: Protein Measurement with the Folin Phenol Reagent, J Biol Chem 193:265-275, 1951.[Free Full Text]
- Hay, D.I. and Grn, P.: Inhibitor of Calcium-phosphate Precipitation in Human Whole Saliva. In: Microbial Aspects of Dental Caries, Stiles, H.M., Loesche, W.J., and O'Brien, T.C., Eds., Sp. Suppl. Microbiol. Abstr., Information Retrieval, Inc., 1976, pp. 143-150.
- Bernardi, G. and Kawasaki, T.: Chromatography of Polypeptides and Proteins on Hydroxyapatite Columns, Biochim Biophys Acta 160:301-310, 1968.[Medline]
[Order article via Infotrieve]
- Hay, D.I. and Belensz, D.: The Identification of Human Proline-rich Proteins as Inhibitors of Calcium-phosphate Precipitation, IADR Progr & Abst 56:No. 74, 1977.
- Hay, D.I. and Moreno, E.C.: Macromolecular Inhibitors of Calcium Phosphate Precipitation in Human Saliva. Their Roles in Providing a Protective Environment for the Teeth. In: Saliva and Dental Caries, Kleinberg, I., Ellison, S.A., and Mandel, I.D., Eds., Sup. Suppl. Microbiol. Abstr., Information Retrieval, Inc., 1979, pp. 45-58.
- Moreno, E.C.; Varughese, K.; and Hay, D.I.: Effect of Human Salivary Proteins on the Precipitation Kinetics of Calcium Phosphate, Calcif Tissue Int 28:7-16, 1979.[CrossRef][Medline]
[Order article via Infotrieve]
Journal of Dental Research, Vol. 61, No. 2,
397-399 (1982)
DOI: 10.1177/00220345820610020601
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