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Increased Collagen Synthesis by Gingival Fibroblasts Derived from a Papillon-Lefevre Patient
H.S. Cheung
Rheumatology Section, Department of Medicine, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226
R.K. Landow
Department of Medicine (Dermatology), Los Angeles County, University of Southern California School of Medicine, Los Angeles, California 90033
M. Bauer
Department of Medicine (Dermatology), Los Angeles County, University of Southern California School of Medicine, Los Angeles, California 90033
Both skin and gingival fibroblasts in the Papillon-Lefévre patient synthesized Type I and Type III collagen in a ratio very similar to fibroblasts of control cells. The only abnormality appeared to be elevated levels of collagen and protein synthesis by gingival cells derived from the Papillon-Lefévre patient.
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Journal of Dental Research, Vol. 61, No. 2,
378-381 (1982)
DOI: 10.1177/00220345820610020101

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