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Relationship Between Frequency of Pilocarpine Administration and Salivary IgA Level
D.J. Smith
Department of Immunology, Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
M.A. Taubman
Department of Immunology, Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
J.L. Ebersole
Department of Immunology, Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
W. King
Department of Immunology, Forsyth Dental Center, 140 The Fenway, Boston, Massachusetts 02115
The effect of repetitive administration of pilocarpine nitrate on the salivary volume and salivary IgA concentration was studied in the NIH white hamster. One and one-half to three-fold increases in salivary volume, coupled with decreases of 1/3 to 2/3 in IgA concentration, occurred as the frequency of administration of pilocarpine increased.
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Journal of Dental Research, Vol. 61, No. 12,
1451-1453 (1982)
DOI: 10.1177/00220345820610121601

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