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Journal of Dental Research
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The Effect of Prostaglandins on Experimental Tooth Movement in Monkeys (Macaca fuscata)

K. Yamasaki

Department of Orthodontics, Showa University Dental Hospital, Ohta-ku, Kitasenzoku 2-1-1, Tokyo 145, Japan

Y. Shibata

Department of Orthodontics, Showa University Dental Hospital, Ohta-ku, Kitasenzoku 2-1-1, Tokyo 145, Japan

T. Fukuhara

Department of Orthodontics, Showa University Dental Hospital, Ohta-ku, Kitasenzoku 2-1-1, Tokyo 145, Japan

Local administrations of prastaglandins E1 or E2 combined with orthodontic tooth movemerat can approximately double the rate of tooth movement in monkeys compared to that of the control. Macroscopically, no side-effect was observed in the gingiva and associated structures.

REFERENCES

  • Yamasaki, K.; Miura, F.; and Suda, T.: Prostaglandin as a Mediator of Bone Resorption Induced by Experimental Tooth Movement in Rats, J Dent Res 59:1635-1642, 1980.[Abstract/Free Full Text]
  • Davidovitch, Z. and Shanfeld, J.L.: Prostaglandin E2 (PGE2) Levels in Alveolar Bone of Orthodontically-treated Cats, IADR Progr & Abst 59:No. 977, 1980.
  • Chumbley, A.B. and Tuncay, O.C.: The Effects of Indomethacin on the Rate of Tooth Movement in Cats, IADR Progr & Abst 60:No. 596, 1981.
  • Vane, J.R.: Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs, Nature New Biol 23: 232-235, 1971.
  • Goodson, J.M.; McClatchy, K.; and Revell, C.: Prostaglandin-induced Resorption of Adult Rat Calvarium, J Dent Res 53:670-677, 1974.[Abstract/Free Full Text]
  • Reitan, K.: Tissue Behavior During Orthodontic Tooth Movement, Am J Orthod 46:881-900, 1960.[CrossRef]
  • Reitan, K.: Effects of Force Magnitude and Direction of Tooth Movement on Different Alveolar Bone Type, Angle Orthod 34:244-255, 1964.
  • Kamata, M.: Effects of Parathyroid Hormone on Tooth Movement in Rats, Bull Tokyo Med Dent Univ 19:411-425, 1972.[Medline] [Order article via Infotrieve]
  • Midgett, R.; Shaye, R.; and Fruge, J.F.: The Effect of Altered Bone Metabolism on Orthodontic Tooth Movement, Am J Orthod 80:256-262, 1981.[CrossRef][Medline] [Order article via Infotrieve]
  • Yamasaki, K.: Effects of Vitamin D on Orthodontic Tooth Movement in Rats, J Stomatol Soc Jpn 43:41-63, 1976.
  • Piper, P.J.; Vane, J.R.; and Wyllie, H.J.: Inactivation of Prostaglandins by the Lungs, Nature 225:600, 1970.[CrossRef][Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 61, No. 12, 1444-1446 (1982)
DOI: 10.1177/00220345820610121401


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This Article
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