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Journal of Dental Research
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Effect of Soluble Calcium on Fluoride Uptake By Enamel From Sodium Monofluorophosphate

J.R. Mellberg

Colgate-Palmolive Research Center, Piscataway, New Jersey 08854

W.G. Chomicki

Colgate-Palmolive Research Center, Piscataway, New Jersey 08854

The fluoride uptake by sound, acid-etched and artificial white spot lesions treated with sodium monofluorophosphate in dentifrice slurries, abrasive slurries, or calcium chloride solutions was determined. Fluoride uptake by sound enamel decreased in the presence of soluble calcium; however, uptake by etched and white spot enamel was greatly enhanced. The optimum Ca:MFP molar ratio was 0.5. Because fluorine-containing dentifrices probably inhibit dental caries by interaction with white spots or at the initial stage of acid-attack, the soluble calcium contained in saliva or a dentifrice might enhance the anti-caries effect of monofluorophosphate.

REFERENCES

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  • Noren, B. and Harse, C.: The Stability of the Monofluorophosphate and Fluoride Ions in Dentifrice Containing Calcium Carbonate, J Soc Cosmet Chem 25:3-11, 1974.
  • Ericsson, Y.: Fluoride in Dentifrices. Investigations Using Radioactive Fluorine, Acta Odontol Scand 19:41-77, 1961.[CrossRef][Medline] [Order article via Infotrieve]
  • Rowley, H.H. and Stuckey, J.E.: Preparation and Properties of Calcium Monofluorophosphate Dihydrate, J Am Chem Soc 78:4262-4263, 1956.[CrossRef]
  • Forward, G.C.: Action and Interaction of Fluoride in Dentifrices, Community Dent Oral Epidemiol 8:257-266, 1980.[CrossRef][Medline] [Order article via Infotrieve]
  • Hefferren, J.J.; Mellberg, J.R.; Zimmerman, M.; Rubin, A.M.; and Cosca, L.J.: Primary Bovine Teeth - An Interesting Substrate for Dental Studies, Abstr., 23rd ORCA Congr., Szeged, 1975.
  • Zahradnik, R.T. and Moreno, E.C.: In vitro Enamel Demineralizations by Streptococcus mutans in the Presence of Salivary Pellicles, J Dent Res 56:1107-1110, 1977.[Abstract/Free Full Text]
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  • Mellberg, J.R.; Laakso, P.V.; and Nicholson, C.R.: The Acquisition and Loss of Fluoride by Topically Fluoridated Tooth Enamel, Arch Oral Biol 11:1213-1220, 1966.[CrossRef][Medline] [Order article via Infotrieve]
  • Ingram, G.S.: The Reaction of Monofluorophosphate with Apatite, Caries Res 6:1-15, 1972.[Medline] [Order article via Infotrieve]
  • Ingram, G.S.: Some Factors Affecting the Interaction of Hydroxyapatite with Sodium Monofluorophosphate, Caries Res 7:315-323, 1973.[Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 61, No. 12, 1394-1396 (1982)
DOI: 10.1177/00220345820610120201


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J.R. Mellberg, I.D. Petrou, M. Deutchman, and N. Grote
The Effects of 1% Pyrophosphate and 0.02% Sodium Fluoride on Artificial Caries Lesions in vivo
Journal of Dental Research, December 1, 1988; 67(12): 1461 - 1465.
[Abstract] [PDF]


This Article
Right arrow Abstract Freely available
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Right arrow Articles by Mellberg, J.R.
Right arrow Articles by Chomicki, W.G.
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PubMed
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Right arrow Articles by Mellberg, J.R.
Right arrow Articles by Chomicki, W.G.
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*Compound via MeSH
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Hazardous Substances DB
*CALCIUM COMPOUNDS
*CALCIUM, ELEMENTAL
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