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Journal of Dental Research
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Clinical Science

Adherence of Streptococcus sanguis to Salivary Mucin Bound to Glass

M.W. Stinson

Departments of Microbiology, Oral Biology, and Endodontics, Schools of Medicine and Dentistry, State University of New York at Buffalo, Buffalo, New York 14214

M.J. Levine

Departments of Microbiology, Oral Biology, and Endodontics, Schools of Medicine and Dentistry, State University of New York at Buffalo, Buffalo, New York 14214

J.M. Cavese

Departments of Microbiology, Oral Biology, and Endodontics, Schools of Medicine and Dentistry, State University of New York at Buffalo, Buffalo, New York 14214

A. Prakobphol

Departments of Microbiology, Oral Biology, and Endodontics, Schools of Medicine and Dentistry, State University of New York at Buffalo, Buffalo, New York 14214

P.A. Murray

Departments of Microbiology, Oral Biology, and Endodontics, Schools of Medicine and Dentistry, State University of New York at Buffalo, Buffalo, New York 14214

L.A. Tabak

Departments of Microbiology, Oral Biology, and Endodontics, Schools of Medicine and Dentistry, State University of New York at Buffalo, Buffalo, New York 14214

M.S. Reddy

Departments of Microbiology, Oral Biology, and Endodontics, Schools of Medicine and Dentistry, State University of New York at Buffalo, Buffalo, New York 14214

This study demonstrated that human submandibular-sublingual saliva (HSMSL) provided a better substrate than did whole saliva or parotid saliva for the binding of Streptococcus sanguis in a glass adherence assay. Additional evidence indicated that the lower molecular weight salivary mucin in HSMSL was involved in these interactions. Mucin's sialic acid residues were found to play a major role in mediating the binding of certain strains of Streptococcus sanguis.

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Journal of Dental Research, Vol. 61, No. 12, 1390-1393 (1982)
DOI: 10.1177/00220345820610120101


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