This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Weigel, R.J. Articles by Nahmias, A.J. Search for Related Content PubMed PubMed Citation Articles by Weigel, R.J. Articles by Nahmias, A.J. Social Bookmarking                         What's this?

The Effect of Herpes Virus Infection on the Membrane Potential of Parotid Acinar Cells

Departments of Periodontology and Pediatrics, Emory University Schools of Dentistry and Medicine, Atlanta, Georgia 30322

M.E. Fritz

Departments of Periodontology and Pediatrics, Emory University Schools of Dentistry and Medicine, Atlanta, Georgia 30322

A.J. Nahmias

Departments of Periodontology and Pediatrics, Emory University Schools of Dentistry and Medicine, Atlanta, Georgia 30322

Monolayers of feline parotid acinar cells were infected with feline rhinotracheitis herpes virus. Membrane potentials and input resistances were measured before and during infection. Uninfected acinar cells had an average membrane potential of -51 m V and resistances from 6 to 120 mega-ohms; cells infected for more than 18 h had an average membrane potential of -19 mV and resistances from 30 to 100 mega-ohms. The time course of the decrease in membrane potential was studied and was found to commence about ten to 14 h after infection.

REFERENCES

• Fritz, M.E. and Nahmias, A.J.: Reversed Polarity in Transmembrane Potentials of Cells Infected with Herpes Viruses, Proc Soc Exp Biol Med 139:1159-1161, 1972.[CrossRef][Medline] [Order article via Infotrieve]
• Fritz, M.E.; Nahmias, A.J.; and Naib, Z.M.: Transmembrane Potential Changes in Cat Parotid Glands Infected with Feline Herpes Virus, J Dent Res 53:766, 1974.[Free Full Text]
• Fritz, M.E. and Botelho, S.Y.: Membrane Potentials in the Unstimulated Parotid Gland of the Cat, Am J Physiol 216:1180-1183, 1969.[Free Full Text]
• Fritz, M.E.; Laveau, P.; Nahmias, A.J.; Weigel, R.J.; and Lee, F.: Primary Cultures of Feline Acinar Cells: Dissociation, Culturing, and Viral Infection, Am J Physiol 239: G288-294, 1980.
• Shipkey, F.H.; Erlandson, R.A., Bailey, R.B.; Babcock, V.I.; and Southam, C.M.: Growth of Herpes Simplex in Tissue Culture, Exp Molec Path 6:39-67, 1969.
• Smith, J.D. and DeHarven, E.: Herpes Simplex Virus and Human Cytomegalovirus Replication in Wl-38 Cells. I. Sequence of Viral Replication, J Virol 12:919-930, 1973.
• Wilson, W.A. and Goldner, M.M.: Voltage Clamping with a Single Microelectrode, J Neurobiol 6:411-422, 1975.[CrossRef][Medline] [Order article via Infotrieve]
• Poulsen, J.H. and Williams, J.A.: Effects of the Calcium lonophore A23187 on Pancreatic Acinar Cell Membrane Potentials and Amylase Release, J Physiol (London) 264:323-339, 1977.[Abstract/Free Full Text]
• Roberts, M.L. and Petersen, O.H.: Membrane Potential and Resistance Changes Induced in Salivary Gland Acinar Cells by Micro-iontophoretic Application of Acetylcholine and Adrenergic Agonists, J Membr Biol 39:297-312, 1978.[CrossRef][Medline] [Order article via Infotrieve]
• Pedersen, G.L. and Petersen, O.H.: Membrane Potential Measurement in Parotid Acinar Cells, J Physiol (London) 234:217-227, 1973.[Abstract/Free Full Text]
• Petersen, O.H.: Electrophysiology of Mammalian Gland Cells, Physiol Rev 56: 535-577, 1976.[Abstract/Free Full Text]
• KamiyaT.;Ben-Porat T.; and Kaplan, A.S.: Control of Certain Aspects of the Infective Process by Progeny Viral DNA, Virology 26:577-589, 1965.[CrossRef][Medline] [Order article via Infotrieve]
• Wagner, E.K. and Roizman, B.: Ribonucleic Acid Synthesis in Cells Infected with Herpes Simplex Virus. I. Patterns of Ribonucleic Acid Synthesis in Productively Infected Cells, J Virol 4: 36-46, 1969.[Abstract/Free Full Text]
• Hammer, M.G. and Sheridan, J.D.: Electrical Coupling and Dye Transfer Between Acinar Cells in Rat Salivary Glands, J Physiol (London) 275:495-505, 1978.[Abstract/Free Full Text]
• Shrier, A.; Nahmias, A.J.; and DeHaan, R.L.: Herpes Virus Infection Alters Electrical Parameters of Heart Cell Aggregates, Am J Physiol 234:C170-C176, 1978.[Medline] [Order article via Infotrieve]

Journal of Dental Research, Vol. 60, No. 12, 1983-1986 (1981)
DOI: 10.1177/00220345810600121001


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This Article Abstract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Weigel, R.J. Articles by Nahmias, A.J. Search for Related Content PubMed PubMed Citation Articles by Weigel, R.J. Articles by Nahmias, A.J. Social Bookmarking                         What's this?